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Item type:Publication, Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation(2017)Scopus© Citations 27 2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe pertussis: State of the art(2012)1Scopus© Citations 17 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Sífilis congénita: presentación como shock séptico después del período neonatal(2012)6Scopus© Citations 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: A feasibility study(2012)3Scopus© Citations 31 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure(2012)Scopus© Citations 31 12 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Surfactant deactivation in a pediatric model induces hypovolemia and fluid shift to the extravascular lung compartment(2012); Tatiana SalomónSurfactant deficiency is the pivotal abnormality in Neonatal and Acute Respiratory Distress Syndrome. Surfactant deactivation can produce hypoxemia, loss of lung compliance, and pulmonary edema, but its circulatory consequences are less understood. Objective To describe the sequential hemodynamic changes and pulmonary edema formation after surfactant deactivation in piglets. Methods: Surfactant deactivation was induced by tracheal instillation of polysorbate 20 in 15 anesthetized and mechanically ventilated Large White piglets. The hemodynamic consequences of surfactant deactivation were assessed at 30, 120, and 240 min by transpulmonary thermodilution and traditional methods. Results: Surfactant deactivation caused hypoxemia, reduced lung compliance, and progressively increased lung water content (P < 0.01). Early hypovolemia was observed, with reductions of the global end-diastolic volume and stroke volume (P < 0.05). Reduced cardiac output was observed at the end of the study (P < 0.05). Standard monitoring was unable to detect these early preload alterations. Surprisingly, the bronchoalveolar protein content was greatly increased at the end of the study compared with baseline levels (P < 0.01). This finding was inconsistent with the notion that the pulmonary edema induced by surfactant deactivation was exclusively caused by high surface tension. Conclusions: Hypovolemia develops early after surfactant deactivation, in part due to the resulting fluid shift from the intravascular compartment to the lungsScopus© Citations 5 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Can acute renal failure be complicated by renal compartment syndrome? Renewed view of an old idea(2013)Scopus© Citations 5 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Characteristics of Medically Transported Critically Ill Children with Respiratory Failure in Latin America: Implications for Outcomes(2021); Maria J. Nuñez<jats:title>Abstract</jats:title><jats:p>Several challenges exist for referral and transport of critically ill children in resource-limited regions such as Latin America; however, little is known about factors associated with clinical outcomes. Thus, we aimed to describe the characteristics of critically ill children in Latin America transferred to pediatric intensive care units for acute respiratory failure to identify risk factors for mortality. We analyzed data from 2,692 patients admitted to 28 centers in the Pediatric Collaborative Network of Latin America Acute Respiratory Failure Registry. Among patients referred from another facility (773, 28%), nonurban transports were independently associated with mortality (adjusted odds ratio = 9.4; 95% confidence interval: 2.4–36.3).</jats:p>4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS(2011)Scopus© Citations 26 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury(2013); Tatiana Salomón15Scopus© Citations 17