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Item type:Publication, Pelvic Floor Prehabilitation for Prevention of Low Anterior Resection Syndrome: Insights From a Randomized Trial (
<scp>CARRET</scp>
Study)(Wiley, 2026-02-10); ;Luz Alejandra Lorca ;Marta Pizarro ;Gonzalo RebolledoMonica Martinez‐Mardones<jats:title>ABSTRACT</jats:title> <jats:sec> <jats:title>Objectives</jats:title> <jats:p>To assess the effectiveness of presurgical and postsurgical pelvic floor physiotherapy on the bowel symptoms and anorectal function of patients with rectal cancer undergoing LAR.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>Randomized controlled trial. The sample included 14 patients undergoing LAR, with 3 months after ileostomy reversal follow‐up. Intervention: Pelvic floor physiotherapy (pelvic floor exercises, biofeedback, balloon training, and health education); one session before LAR, four sessions before ostomy reversal, and five to eight sessions after reversal. Outcomes: Bowel function assessed with the International Consultation on Incontinence Questionnaire Bowel Module and LARS score, and high‐resolution anorectal manometry.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p> Only 25% of the intended sample was recruited, limiting the ability to assess the intervention's effectiveness. Data revealed no difference between groups on bowel symptoms (bowel pattern, bowel control, and quality of life) and anorectal function (pressures and sensitivity); <jats:italic>p</jats:italic> > 0.05. Bowel function domains worsened at final assessment, compared to baseline. The mean resting pressure was the most reduced both before LAR (44.3 [SD = 12.0] mmHg) and post LAR (27.2 [SD = 10.7] mmHg). Women were more likely to adhere to the intervention. Despite several implementation barriers, the intervention proved feasible, with higher adherence before tumor resection and lower adherence before ileostomy reversal. </jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Due to the limited sample size, definitive conclusions regarding the effectiveness of pelvic floor prehabilitation for LAR cannot be drawn. The challenges in implementing pelvic floor prehabilitation studies, as illustrated in this research, should be carefully considered.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial Registration</jats:title> <jats:p>ACTRN12620000040965</jats:p> </jats:sec>5 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Psychometric properties of the Chilean version of the quality of life questionnaire for multiple myeloma(2024) ;Luz Alejandra Lorca; ;Camila Peña ;Claudia BarreraMelissa Salazar<jats:p>ABSTRACT Objectives: To evaluate the internal consistency and construct validity of the QLQ-MY20 for assessing the quality of life in multiple myeloma survivors in Chile. Methods: This was a cross-sectional study conducted between March 2020 and December 2022. It involved 118 individuals from two public hospitals. The QLQ-C30 and QLQ-MY20 questionnaires were used. Internal consistency was assessed using Cronbach’s alpha(α), and construct validity was evaluated through hypothesis testing (Mann-Whitney and Spearman correlation). Results: The average age of participants was 67.2 years (SD=9.2). Internal consistency for the complete scale was α=0.779, for the “disease symptoms” dimension α=0.671, for the “side effects of treatments” dimension α=0.538, and for the “future perspective” dimension α=0.670. Four of the five construct validity hypotheses were confirmed: women, individuals with worse performance status, those with pain, and those with worse fatigue showed more symptoms. Conclusions: The Chilean version of the QLQ-MY20 demonstrates adequate internal consistency and construct validity.</jats:p>Scopus© Citations 2 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Spanish version of the ICIQ-Bowel questionnaire among colorectal cancer patients: construct and criterion validity(2023); ;Luz Alejandra Lorca ;Mónica Martinez-Mardones ;Marta Natalia Pizarro-HinojosaGonzalo Sebastián Rebolledo-Diaz<jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>Bowel complaints are very common among patients with colorectal cancer. However, the most used questionnaires for colorectal cancer survivors do not comprehensively comprise bowel symptoms. This study aimed to examine construct and criterion validity, as well as internal consistency, of the Chilean Version of the International Consultation on Incontinence Questionnaire Bowel Module (ICIQ-B) among people with colorectal cancer.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Cross-sectional, validation study performed with 106 colorectal cancer patients from Hospital del Salvador, Chile. Bowel function was assessed with the ICIQ-B. Construct validity was assessed with confirmatory factor analysis and hypothesis testing. Specific items of a quality-of-life questionnaire (EORTC QLQ-CR29) were used to correlate with similar ICIQ-B items for criterion validity. For internal consistency, Cronbach’s alpha was computed.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>For construct validity, the confirmatory factor analysis showed that the three factors model did not fit our data. Meanwhile, hypothesis testing favored the construct validity of the instrument, considering that rectal cancer patients showed worse bowel pattern (p = 0.001), bowel control (p = 0.001) and quality of life (p < 0.001) scores compared to colon cancer patients. In addition, those patients assessed before surgery also presented worse scores bowel control (p = 0.023) and quality of life (p = 0.009) compared to post-surgical patients. Regarding criterion validity, the ICIQ-B items showed a significant correlation with similar QLQ-CR29 items. The internal reliability of the instrument was good (Cronbach’s α = 0.909).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Considering that this questionnaire appraises bowel function in more depth, it is recommended for use in clinical practice and research with colorectal cancer patients.</jats:p> </jats:sec>2Scopus© Citations 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Spanish Translation, Face Validity, and Reliability of the ICIQ-B Questionnaire with Colorectal Cancer Patients(2021); ;Luz Alejandra Lorca ;Mónica Martinez-Mardones ;Paulina BenaventeJorge Plasser<jats:title>Abstract</jats:title><jats:p> Purpose To describe the English-to-Spanish translation process and preliminary psychometric analysis (face validity, cultural adaptation, and test-retest reliability) of the International Consultation on Incontinence Questionnaire – Bowels Module (ICIQ-B) among Chilean colorectal cancer patients.</jats:p><jats:p> Materials and Methods The face validity was studied with 10 colorectal cancer patients, and the test-retest reliability, with 15 patients, 1 month before and 6 months after cancer surgery.</jats:p><jats:p> Results Two rounds of translation/back translation resulted in a Spanish version. The English expression open your bowels was translated as defecar, as it is easily understandable in Spanish. The patients reported that the instrument was easy to answer, with clear instructions, and that it was adequate to appraise their health condition. The test-retest reliability was good (Spearman rho [ρ] ≥ 0.842); only item 15a, the Bristol Stool Scale, obtained a moderate correlation (ρ = 0.639). The patients reported a variety of symptoms, including increased bowel movements, nocturnal bowel movements, fecal urgency, and incontinence.</jats:p><jats:p> Conclusions The first Spanish version of the ICIQ-B was culturally adapted for Chilean colorectal cancer patients, and showed good test-retest reliability. It might be a reference for other Spanish-speaking countries and for patients with other conditions. The ICIQ-B is a robust comprehensive questionnaire for bowel function.</jats:p>16 1Scopus© Citations 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Commentary: Functional bowel complaints and the impact on quality of life after colorectal cancer surgery in the elderly(2023); ;Mónica Belén Martinez-Mardones ;Luz Alejandra LorcaLaura Isabel Solé1Scopus© Citations 1 1