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Author: search.filters.author.Eduard VietaSubject: search.filters.subject.bipolar disorder

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      6Scopus© Citations 16
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    Scopus© Citations 9  2
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      1Scopus© Citations 10  1
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    Emotional intelligence: a comparison between patients after first episode mania and those suffering from chronic bipolar disorder type I
    (2022)
    Cristina Varo
    ;
    Silvia Amoretti
    ;
    Giulio Sparacino
    ;
    Esther Jiménez
    ;
    Brisa Solé
    <jats:title>Abstract</jats:title> <jats:sec id="S0033291721005122_sec_a1"> <jats:title>Background</jats:title> <jats:p>Deficits in emotional intelligence (EI) were detected in patients with bipolar disorder (BD), but little is known about whether these deficits are already present in patients after presenting a first episode mania (FEM). We sought (i) to compare EI in patients after a FEM, chronic BD and healthy controls (HC); (ii) to examine the effect exerted on EI by socio-demographic, clinical and neurocognitive variables in FEM patients.</jats:p> </jats:sec> <jats:sec id="S0033291721005122_sec_a2" sec-type="methods"> <jats:title>Methods</jats:title> <jats:p>The Emotional Intelligence Quotient (EIQ) was calculated with the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT). Performance on MSCEIT was compared among the three groups using generalized linear models. In patients after a FEM, the influence of socio-demographic, clinical and neurocognitive variables on the EIQ was examined using a linear regression model.</jats:p> </jats:sec> <jats:sec id="S0033291721005122_sec_a3" sec-type="results"> <jats:title>Results</jats:title> <jats:p>In total, 184 subjects were included (FEM <jats:italic>n</jats:italic> = 48, euthymic chronic BD type I <jats:italic>n</jats:italic> = 75, HC <jats:italic>n</jats:italic> = 61). BD patients performed significantly worse than HC on the EIQ [mean difference (MD) = 10.09, standard error (<jats:sc>s.e.)</jats:sc> = 3.14, <jats:italic>p</jats:italic> = 0.004] and on the understanding emotions branch (MD = 7.46, <jats:sc>s.e.</jats:sc> = 2.53, <jats:italic>p</jats:italic> = 0.010). FEM patients did not differ from HC and BD on other measures of MSCEIT. In patients after a FEM, EIQ was positively associated with female sex (<jats:italic>β</jats:italic> = −0.293, <jats:italic>p</jats:italic> = 0.034) and verbal memory performance (<jats:italic>β</jats:italic> = 0.374, <jats:italic>p</jats:italic> = 0.008). FEM patients performed worse than HC but better than BD on few neurocognitive domains.</jats:p> </jats:sec> <jats:sec id="S0033291721005122_sec_a4" sec-type="conclusions"> <jats:title>Conclusions</jats:title> <jats:p>Patients after a FEM showed preserved EI, while patients in later stages of BD presented lower EIQ, suggesting that impairments in EI might result from the burden of disease and neurocognitive decline, associated with the chronicity of the illness.</jats:p> </jats:sec>
    Scopus© Citations 4  2
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    Making sense of DSM-5 mania with depressive features
    (2015)
    María Reinares
    ;
    Caterina del Mar Bonnín
    ;
    Diego Hidalgo-Mazzei
    ;
    Juan Undurraga  
    ;
    Maria Mur
    <jats:sec><jats:title>Objective:</jats:title><jats:p> The assessment of the depressive component during mania has become critical for the accurate diagnosis of mixed states, which were defined very narrowly in the past classification systems before Diagnostic and Statistical Manual of Mental Disorders (5th ed.). The aim of this study was to compare socio-demographic, clinical and therapeutic characteristics, as well as clinical and functional outcomes, between manic patients with and without mixed features to validate the relevance of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) mixed specifier. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> This is a subanalysis of a multicentre naturalistic study MANía Aguda y COnsumo de Recursos (acute mania and health resource consumption [MANACOR]) on the burden of mania in bipolar patients from four hospitals in Catalonia (Spain). The sample consisted of 169 adult patients presenting a manic episode and systematically assessed during a 6-month period. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 27% ( n = 46/169) of manic patients showed mixed features. Total number of episodes ( p = 0.027), particularly depressive and mixed, was greater in manic patients with mixed features, as well as depressive onset ( p = 0.018), suicide ideation ( p = 0.036), rapid cycling ( p = 0.035) and personality disorders ( p = 0.071). In contrast, a higher percentage of pure manic subjects were inpatients ( p = 0.035), started the illness with mania ( p = 0.018) and showed family history of bipolar disorder ( p = 0.037), congruent psychotic symptoms ( p = 0.001) and cannabis use ( p = 0.006). At baseline, pure manic patients received more risperidone ( p = 0.028), while mixed patients received more valproate ( p = 0.049) and antidepressants ( p = 0.005). No differences were found in syndromic recovery at the end of the study. However, depressive change was higher in the mixed group ( p = 0.010), while manic change was higher in the pure manic group ( p = 0.029). At the end of follow-up, the group with mixed features showed a significant trend towards higher psychosocial dysfunction. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> A total of 27% of manic patients showed mixed features. Groups differed regarding clinical characteristics, course of illness, psychosocial functioning, prescribed treatment and symptom progress. Depressive symptoms in mania should be routinely assessed and considered to guide treatment. </jats:p></jats:sec>
      1Scopus© Citations 25
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    Predictors of functional outcome after a manic episode
    (2015)
    C. Mar Bonnín
    ;
    María Reinares
    ;
    Diego Hidalgo-Mazzei
    ;
    Juan Undurraga  
    ;
    Maria Mur
      12Scopus© Citations 18
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    Psychoeducation in bipolar disorder with a SIMPLe smartphone application: Feasibility, acceptability and satisfaction
    (2016)
    Diego Hidalgo-Mazzei
    ;
    Ainoa Mateu
    ;
    María Reinares
    ;
    Andrea Murru
    ;
    Caterina del Mar Bonnín
      16Scopus© Citations 89
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    Risk factors for rapid cycling in bipolar disorder
    (2015)
    Marc Valentí
    ;
    Isabella Pacchiarotti
    ;
    Juan Undurraga  
    ;
    C Mar Bonnín
    ;
    Dina Popovic
      15Scopus© Citations 35
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      22Scopus© Citations 55
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    Clinical characterization of rapid cycling bipolar disorder: Association with attention deficit hyperactivity disorder
    (2018)
    Alberto Aedo
    ;
    Andrea Murru
    ;
    Raúl Sanchez
    ;
    Iria Grande
    ;
    Eduard Vieta
      20Scopus© Citations 16