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    Item type:Publication,
    Chorionic Bump: An Early Ultrasound Marker for Adverse Obstetric Outcome
    (2019)
    María Carolina Silva
    ;
    Alvaro Sepúlveda-Martínez
    ;
    Rodolfo Guíñez
    ;
    María Teresa Haye
    ;
    Mauro Parra-Cordero
    <jats:p>&lt;b&gt;&lt;i&gt;Backgrounds/Aims:&lt;/i&gt;&lt;/b&gt; To assess the perinatal outcome of pregnancies with chorionic bump detected at the first trimester of pregnancy. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; This was a nested case-control study of pregnancies with chorionic bump identified at the first trimester ultrasound that was performed from October 2014 and October 2016. The control group consisted of the following 5 unaffected pregnancies after each case. From the first trimester ultrasound, maternal and perinatal characteristics were obtained and stored in a dedicated database. The primary outcome was defined as the presence of an alive new-born. Secondary outcome was defined as the presence of a composite adverse obstetric outcome. &lt;b&gt;&lt;i&gt;Results&lt;/i&gt;&lt;/b&gt;: Eleven first trimester pregnancies affected by a chorionic bump and 55 controls were identified. The primary outcome was observed in 72.7 and 89.1% of chorionic bump and controls respectively (&lt;i&gt;p&lt;/i&gt; = 0.2). The secondary outcome was observed in 45.5% of pregnancies with a chorionic bump versus 12.7% in the unaffected group (&lt;i&gt;p&lt;/i&gt; = 0.01). First trimester uterine artery Doppler demonstrated a non-significant trend to be higher in the chorionic bump group. &lt;b&gt;&lt;i&gt;Conclusions:&lt;/i&gt;&lt;/b&gt; The presence of a chorionic bump is associated with a significant higher risk of adverse perinatal outcome.</jats:p>
    Scopus© Citations 11  2