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Item type:Publication, Chorionic Bump: An Early Ultrasound Marker for Adverse Obstetric Outcome(2019) ;María Carolina Silva ;Alvaro Sepúlveda-Martínez ;Rodolfo Guíñez ;María Teresa HayeMauro Parra-Cordero<jats:p><b><i>Backgrounds/Aims:</i></b> To assess the perinatal outcome of pregnancies with chorionic bump detected at the first trimester of pregnancy. <b><i>Methods:</i></b> This was a nested case-control study of pregnancies with chorionic bump identified at the first trimester ultrasound that was performed from October 2014 and October 2016. The control group consisted of the following 5 unaffected pregnancies after each case. From the first trimester ultrasound, maternal and perinatal characteristics were obtained and stored in a dedicated database. The primary outcome was defined as the presence of an alive new-born. Secondary outcome was defined as the presence of a composite adverse obstetric outcome. <b><i>Results</i></b>: Eleven first trimester pregnancies affected by a chorionic bump and 55 controls were identified. The primary outcome was observed in 72.7 and 89.1% of chorionic bump and controls respectively (<i>p</i> = 0.2). The secondary outcome was observed in 45.5% of pregnancies with a chorionic bump versus 12.7% in the unaffected group (<i>p</i> = 0.01). First trimester uterine artery Doppler demonstrated a non-significant trend to be higher in the chorionic bump group. <b><i>Conclusions:</i></b> The presence of a chorionic bump is associated with a significant higher risk of adverse perinatal outcome.</jats:p>Scopus© Citations 11 2