Chorionic Bump: An Early Ultrasound Marker for Adverse Obstetric Outcome
Journal
Gynecologic and Obstetric Investigation
ISSN
0378-7346
1423-002X
Date Issued
2019
Author(s)
María Carolina Silva
Alvaro Sepúlveda-Martínez
Rodolfo Guíñez
María Teresa Haye
Mauro Parra-Cordero
Type
Resource Types::text::journal::journal article
Abstract
<jats:p><b><i>Backgrounds/Aims:</i></b> To assess the perinatal outcome of pregnancies with chorionic bump detected at the first trimester of pregnancy. <b><i>Methods:</i></b> This was a nested case-control study of pregnancies with chorionic bump identified at the first trimester ultrasound that was performed from October 2014 and October 2016. The control group consisted of the following 5 unaffected pregnancies after each case. From the first trimester ultrasound, maternal and perinatal characteristics were obtained and stored in a dedicated database. The primary outcome was defined as the presence of an alive new-born. Secondary outcome was defined as the presence of a composite adverse obstetric outcome. <b><i>Results</i></b>: Eleven first trimester pregnancies affected by a chorionic bump and 55 controls were identified. The primary outcome was observed in 72.7 and 89.1% of chorionic bump and controls respectively (<i>p</i> = 0.2). The secondary outcome was observed in 45.5% of pregnancies with a chorionic bump versus 12.7% in the unaffected group (<i>p</i> = 0.01). First trimester uterine artery Doppler demonstrated a non-significant trend to be higher in the chorionic bump group. <b><i>Conclusions:</i></b> The presence of a chorionic bump is associated with a significant higher risk of adverse perinatal outcome.</jats:p>
Subjects
chorionic bump
;
first trimester
;
perinatal outcome
;
risk factor
;
adult
;
biomarkers
;
case-control studies
;
chorion
;
female
;
humans
;
pregnancy
;
pregnancy outcome
;
pregnancy trimester, first
;
ultrasonography, doppler
;
ultrasonography, prenatal
;
uterine artery
;
biological marker
;
adult
;
adverse outcome
;
article
;
birth weight
;
body mass
;
case control study
;
cesarean section
;
chorionic bump
;
controlled study
;
doppler ultrasonography
;
female
;
fetus mortality
;
first trimester pregnancy
;
gestational age
;
gestational sac
;
hematoma
;
human
;
intrauterine growth retardation
;
live birth
;
major clinical study
;
maternal age
;
nullipara
;
preeclampsia
;
pregnancy complication
;
pregnancy outcome
;
pregnancy rate
;
priority journal
;
pulsatility index
;
ultrasound
;
uterine artery
;
chorion
;
diagnostic imaging
;
fetus echography
;
pregnancy