Universidad del Desarrollo

Now showing 1 - 3 of 3

Some of the metrics are blocked by your
consent settings
Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice
(2023)
Daniela Álvarez
;
Macarena Ortiz
;
Gabriel Valdebenito
;
Nicolás Crisosto
;
Bárbara Echiburú
<jats:p>A high-fat diet (HFD) during pregnancy promotes fat accumulation and reduces docosahexaenoic acid (DHA) levels in the liver of the offspring at postnatal ages, which can depend on fetal sex. However, the prenatal mechanisms behind these associations are still unclear. Thus, we analyzed if an HFD alters DHA content and the expression of molecules related to fatty acid (FA) metabolism in the fetal liver. Female C57BL/6 mice were fed a control diet or HFD for 4–6 weeks before pregnancy until the gestational day (GD) 17.5. A subgroup of each diet received DHA (100 mg/Kg) orally from GD 6.5 until 16.5. On GD 17.5, maternal livers, placentas, and livers from male and female fetuses were collected for FA profiling with gas-chromatography and gene expression of molecules related to FA metabolism using qPCR. PPAR-α protein expression was evaluated using Western blot. The gene expression of placental FA transporters was also assessed. An HFD increased eicosapentaenoic acid (EPA) and decreased DHA levels and protein expression of PPAR-α in the fetal livers of both sexes. DHA increased the gene expression of Ppara, Cpt1, and Acsl1 in the livers of female fetuses. Therefore, an HFD reduces DHA levels and PPAR-α, a master regulator of gene expression, in the fetal liver. In turn, the livers of female fetuses seem to be more sensitive to DHA action.</jats:p>
Scopus© Citations 2
Some of the metrics are blocked by your
consent settings
Effects of Occupational Therapy Program Based on Active Meditation on Hair Cortisol Levels in Undergraduate Healthcare Students
(2022)
Alejandra Espinosa
;
Rodolfo Morrison
;
Diego Gonzalez
;
Juan Jamardo
;
Federico Fortuna
<jats:p>Context. Meditation incorporation helps to fight against disorders such as depression, stress, and anxiety. Specifically, few studies have studied Osho’s Active Meditation on young people, but observed evidence using passive meditation shows that it could improve stress well-management, emotional control, and other mental unhealthy conditions. Goal. The present study pointed to evaluate the results of an occupational therapy program centered on active meditation on hair cortisol concentration in a sample of undergraduate healthcare students. Methods. Undergraduate students from the University of Chile’s health careers were divided at random into control (<jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>n</mi> <mo>=</mo> <mn>7</mn> </math> </jats:inline-formula>) and treated groups (<jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M2"> <mi>n</mi> <mo>=</mo> <mn>15</mn> </math> </jats:inline-formula>). The treated group participated in an active meditation program once a week for three months. This treatment included different techniques such as Chakra Sounds, Nataraj, Mandala, Kundalini, Devavani, Gourishankar, and Nadabrahma. Hair samples were taken before and after the treatment period to measure cortisol. Results. The control group increased cortisol level <jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M3"> <mn>168.9</mn> <mo>±</mo> <mn>76.8</mn> </math> </jats:inline-formula> pg/mg compared with initial levels. The treated group shows a decrease of initial cortisol values in <jats:inline-formula> <math xmlns="http://www.w3.org/1998/Math/MathML" id="M4"> <mn>28.5</mn> <mo>±</mo> <mn>12.8</mn> </math> </jats:inline-formula> pg/mg after meditation protocol application. Conclusions. Blending active meditation in students’ daily routine through occupational therapy intervention might prevent undergraduate students’ stress in healthcare careers.</jats:p>
8Scopus© Citations 3
Some of the metrics are blocked by your
consent settings
Efectos de la meditación activa en indicadores físicos y psicoemocionales de estrés en estudiantes universitarios en Chile. Un estudio piloto
(2020)
Rodolfo Morrison
;
Carmen Paz-Díaz
;
Pamela Gutiérrez
;
Carla Frías
;
Alejandra Espinosa
<jats:p>Introducción. Las múltiples exigencias académicas a las que los estudiantes universitarios se enfrentan les generan altos niveles de estrés; si bien el estrés puede ayudarles a afrontar tales exigencias, en muchos casos este puede causarles diversos problemas de salud.Objetivo. Evaluar si la implementación de la meditación activa en la rutina diaria de estudiantes universitarios de las ciencias de la salud tiene un efecto en sus indicadores físicos y psicoemocionales.Materiales y métodos. Estudio piloto exploratorio y cuantitativo realizado en una muestra de 22 estudiantes universitarios que aceptaron participar en un curso electivo de meditación activa de 3 meses (18 sesiones). A los participantes se les solicitó diligenciar el Cuestionario de Percepción Global de Estado (CPGE) ex ante y ex post al curso.Resultados. 18 participantes completaron el CPGE ex ante y ex post, pero solo 16 fueron válidos para el procesamiento de datos. La mayoría de estudiantes reportó una mejora respecto a su percepción sobre cómo enfrentar diferentes situaciones estresantes luego de completar el curso, por ejemplo, el 87.5% manifestó permanecer en un estado de relajación en situaciones estresantes; el 81%, una disminución del agotamiento mental, y el 81%, un mejor manejo de las situaciones estresantes.Conclusiones. La incorporación de la meditación activa en la rutina diaria de estos estudiantes disminuyó sus indicadores físicos y psicoemocionales de estrés, por lo que es necesario realizar nuevos estudios con muestras más grandes que permitan confirmar el efecto positivo de este tipo de cursos en la salud de los estudiantes universitarios, lo que sin duda repercutirá en un mejor rendimiento académico producto de un mejor estado mental.</jats:p>
34Scopus© Citations 1

CRIS

Browse

Filters

Settings

Sort By

Results per page

Search Results