Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors - Christopher Fitzpatrick; Maximiliano F. Bendek; Macarena Briones; Nicole Farfán; Valeria A. Silva; Gino Nardocci; Martín Montecino; Anne Boland; Jean-François Deleuze; Jaime Villegas; Claudio Villota; Verónica Silva; et al. (My University, 2019)
Keywords: long noncoding rnas; microrna-binding-sites; messenger-rnas; expression; survivin; asncmtrna-2; regulator; 5'-utr; cdk1; animals; antagomirs; apoptosis; breast neoplasms; cdc2 protein kinase; cell cycle checkpoints; cell line, tumor; cell proliferation; cyclin b1; cyclin d1; down-regulation; female; humans; mice; mice, inbred balb c; micrornas; mitochondria; rna interference; rna, long noncoding; rna, small interfering; andes 1537; antineoplastic agent; antisense oligonucleotide; cell cycle protein; cyclin b1; cyclin d1; mitochondrial rna; survivin; unclassified drug; untranslated rna; antagomir; cdk1 protein, human; cyclin b1; cyclin d1; cyclin dependent kinase 1; long untranslated rna; microrna; small interfering rna; animal experiment; animal model; antineoplastic activity; apoptosis; article; breast cancer; breast cancer cell line; cancer inhibition; cell cycle arrest; cell cycle progression; cell proliferation; comparative study; controlled study; dna fragmentation; down regulation; genetic transfection; human; human cell; in vivo study; mda-mb-231 cell line; mouse; nonhuman; priority journal; protein expression; rna sequence; tumor cell; tumor growth; tumor xenograft; upregulation; western blotting; zr-75-1 cell line; animal; apoptosis; bagg albino mouse; breast tumor; cell cycle checkpoint; chemistry; female; genetics; metabolism; mitochondrion; pathology; rna interference; tumor cell line