M.J. YañezT. MarínE. BalboaKLEIN POSTERNACK, ANDRES DAVIDANDRES DAVIDKLEIN POSTERNACKA.R. AlvarezS. Zanlungo2022-10-032022-10-032020Yañez, M. J., Marín, T., Balboa, E., Klein, A. D., Alvarez, A. R., & Zanlungo, S. (2020). Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1866(10), 165875. https://doi.org/10.1016/j.bbadis.2020.165875http://hdl.handle.net/11447/4146https://investigadores.udd.cl/handle/123456789/367310.1016/j.bbadis.2020.1658752-s2.0-85086603125WOS:000559983700019c-ablcholesterolgaucherlysosomal storage diseaselysosomeniemann-picksphingolipidsbraincholesterolgaucher diseaseglucosylceramidasehumansintracellular signaling peptides and proteinslipid metabolismlysosomesmutationneuronsniemann-pick disease, type aniemann-pick disease, type csignal transductionsphingolipidsvesicular transport proteinsarimoclomolimatinibmiglustatsphingomyelin phosphodiesterasecholesterolgba protein, humanglucosylceramidasenpc1 protein, humannpc2 protein, humansignal peptidesphingolipidvesicular transport proteinapoptosisautophagy (cellular)calcium homeostasiscell activationcell viabilitydisorders of mitochondrial functionsendoplasmic reticulum stressendosomeenzyme activitygaucher diseasegene mutationhumanlipid storageliver injuryloss of function mutationlysosome storage diseasenecroptosisnerve degenerationniemann pick diseaseoxidative stresspathogenesispriority journalreviewsignal transductionbraincytologygaucher diseasegeneticslipid metabolismlysosomemetabolismmutationnerve cellniemann pick diseasepathologyResource Types::text::journal::journal article