Lorenzo Reyes-BozoEduardo VyhmeisterGabriel G. CastaneJuan ChirinosJeannette ZárragaClaudia Sandoval-YáñezVALDÉS GONZÁLEZ, HÉCTOR MOISÉSHÉCTOR MOISÉSVALDÉS GONZÁLEZ2025-06-182025-06-182025-05-07https://investigadores.udd.cl/handle/123456789/1112410.3390/w17091402Arsenic contamination in water remains a critical global challenge, particularly in rural and resource-limited regions. Clays have been widely studied as cost-effective and efficient adsorbents for arsenic removal. This systematic review provides a comprehensive analysis of the application of clays in arsenic adsorption, focusing on clay types, operational units, and study methodologies. The review classifies the adsorption mechanisms, highlights key factors influencing adsorption performance—such as pH, ionic strength, and surface modifications—and examines the effectiveness of various modifications. Furthermore, the study categorizes adsorption research into kinetic, iso-thermal, thermodynamic, and efficiency studies, providing insights into the state of the art and the experimental conditions that govern arsenic removal. It also discusses the scalability and practical application of clay-based adsorption technologies, emphasizing gaps in field validation, regeneration studies, and large-scale implementation. The findings highlight the potential of natural and modified clays in arsenic remediation, while underscoring the need for further research to optimize adsorption conditions and enhance sustainability in water treatment systems.adsorption isothermsphysisorptionriver pollutionarsenic adsorptionarsenic contaminationarsenic removalclay typecomprehensive analysiscost effectivecost-efficientglobal challengessystematic literature reviewsystematic reviewadsorptionarsenicclay mineralliterature reviewphysicochemical propertysustainabilitywater treatmentgas adsorptionarsenic adsorptionclay mineralssystematic reviewwater treatmentjournal-article