Characterisation of the pathophysiology of neuropathy and sensory dysfunction in a mouse model of recessive dystrophic epidermolysis bullosa - Daniela Schmidt; Paula Díaz; Daniela Muñoz; Fernanda Espinoza; Alexander Nystrom; FUENTES BUSTOS, MARIA IGNACIA; EZQUER, EDUARDO MARCELO; David L. Bennett; Margarita Calvo (My University, 2022)
Keywords: mouse model; neuropathic pain; neuropathy; rdeb; small-fibre neuropathy; animals; collagen type vii; disease models, animal; epidermolysis bullosa dystrophica; humans; mice; mutation; skin; small fiber neuropathy; activating transcription factor 3; calcitonin gene related peptide; collagen type 7; col7a1 protein, human; collagen type 7; adult; animal experiment; animal model; animal tissue; article; astrocyte; axonal injury; c57bl 6 mouse; cell population; controlled study; epidermolysis bullosa dystrophica; female; glia cell; heat sensitivity; hind paw; hyposensitivity (sensory dysfunction); macrophage; male; mechanical hyperalgesia; microglia; morphology; mouse; mouse model; myelinated nerve; nerve ending; nerve fiber; nerve fiber c; nerve fiber degeneration; nervous system inflammation; neuropathy; nociception; nonhuman; nonmyelinated nerve; pain receptor; pathophysiology; place preference; recessive inheritance; satellite glial cell; scratching; sensory dysfunction; sensory nerve cell; somatosensory system; spinal cord nerve cell; spinal ganglion; thermal hyperalgesia; animal; complication; disease model; genetics; human; metabolism; mutation; pathology; skin; small fiber neuropathy