IDIAQUEZ RIOS, JUAN FRANCISCO

Preferred name
IDIAQUEZ RIOS, JUAN FRANCISCO
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Email
jidiaquez@udd.cl
ORCID
0000-0001-9943-8835
Scopus Author ID
56044663200
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    Evaluación clínica de las Disautonomías
    (2020)
    Juan Idiáquez C
    ;
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    Eduardo Benarroch
    Scopus© Citations 2  14
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    Scopus© Citations 4  1
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    Scopus© Citations 9  1
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    Recessive dystrophic epidermolysis bullosa results in painful small fibre neuropathy
    (2017)
    Sofia von Bischhoffshausen
    ;
    Dinka Ivulic
    ;
    Paola Alvarez
    ;
    Victor C. Schuffeneger
    ;
    Juan Idiaquez  
      54Scopus© Citations 45
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    Assessing diabetic polyneuropathy in Spanish‐speaking patients: Translation and validation of the Toronto Clinical Neuropathy Score
    (2023)
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    Ignacio Acosta
    ;
    Alberto Prat
    ;
    Francesca Gattini
    ;
    Francisca Pino
    <jats:title>Abstract</jats:title><jats:sec><jats:title>Background and Aims</jats:title><jats:p>Diabetic sensorimotor polyneuropathy (DSP) is a common complication of diabetes. The Toronto Clinical Neuropathy Score (TCNS) is a useful tool for detecting DSP. However, it is not available in Spanish. The study aimed to translate and culturally adapt the TCNS and modified (mTCNS) scales into Spanish and evaluate their measurement properties.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A multistep forward‐backward method was used for translation and cultural adaptation. A panel of physicians subjected the final Spanish versions of TCNS and mTCNS (TCÑS, mTCÑS) to cognitive debriefing. Consecutive patients with diabetes mellitus and DSP were recruited from an outpatient clinic, and the TCÑS and mTCÑS were tested for construct validity, along with other measures.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>The internal consistency of both TCÑS and mTCÑS was excellent, as evidenced by Cronbach's Alpha coefficients of 0.83 and 0.85, respectively. Furthermore, there was a robust positive correlation between TCÑS and mTCÑS. In addition, TCÑS was found to exhibit a strong negative correlation with sural sensory nerve action potential amplitude (<jats:italic>r</jats:italic> = −0.9206) and peroneal compound motor action potential amplitude (<jats:italic>r</jats:italic> = −0.729), while demonstrating a positive and strong correlation with the Michigan Neuropathy Screening Instrument (<jats:italic>r</jats:italic> = 0.713).</jats:p></jats:sec><jats:sec><jats:title>Interpretation</jats:title><jats:p>The TCÑS and mTCÑS are reliable and valid translations of the original TCNS. The TCÑS and mTCÑS can be used to diagnose and measure the severity of neuropathy in Spanish‐speaking patients with diabetes.</jats:p></jats:sec>
      9Scopus© Citations 2
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    Response to “Synucleinopathy: Treatment of Supine Hypertension”
    (2021)
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    IDIAQUEZ, JUAN
    ;
    Juan Carlos Casar
    ;
    Italo Biaggioni
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    Epidemiology of Parkinson’s Disease in Chile
    (2021)
    VIAL UNDURRAGA, FELIPE AGUSTIN  
    ;
    DELGADO BECERRA, OROZIMBA IRIS  
    ;
    Francisca Canal
    ;
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    Pedro Chana-Cuevas
    <jats:p>&lt;b&gt;&lt;i&gt;Introduction:&lt;/i&gt;&lt;/b&gt; Parkinson’s disease (PD) is one of the most common neurodegenerative disorders. There is no epidemiological description of PD in Chile and not many descriptions in Latin America. This study aims to describe the incidence and prevalence of PD in Chile. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; The study group was the population on the public health system in Chile between 2010 and 2018 that were registered in the GES system as having PD. Crude and standardized prevalence and incidence were calculated with a 95% confidence interval. &lt;b&gt;&lt;i&gt;Results:&lt;/i&gt;&lt;/b&gt; 33,345 patients were found in the register as confirmed cases with PD. The crude incidence in 2018 was 23.7/100,000; the crude prevalence in 2018 was 160.7/100,000. The male-to-female ratio was 1.03. &lt;b&gt;&lt;i&gt;Conclusion:&lt;/i&gt;&lt;/b&gt; The prevalence and incidence observed in the Chilean population are consistent with studies from other countries. </jats:p>
    Scopus© Citations 8  114
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    Neurogenic Orthostatic Hypotension. Lessons From Synucleinopathies
    (2020)
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    IDIAQUEZ RIOS, JUAN FRANCISCO  
    ;
    Juan Carlos Casar
    ;
    Italo Biaggioni
    <jats:title>Abstract</jats:title> <jats:p>Maintenance of upright blood pressure critically depends on the autonomic nervous system and its failure leads to neurogenic orthostatic hypotension (NOH). The most severe cases are seen in neurodegenerative disorders caused by abnormal α-synuclein deposits: multiple system atrophy (MSA), Parkinson’s disease, Lewy body dementia, and pure autonomic failure (PAF). The development of novel treatments for NOH derives from research in these disorders. We provide a brief review of their underlying pathophysiology relevant to understand the rationale behind treatment options for NOH. The goal of treatment is not to normalize blood pressure but rather to improve quality of life and prevent syncope and falls by reducing symptoms of cerebral hypoperfusion. Patients not able to recognize NOH symptoms are at a higher risk for falls. The first step in the management of NOH is to educate patients on how to avoid high-risk situations and providers to identify medications that trigger or worsen NOH. Conservative countermeasures, including diet and compression garments, should always precede pharmacologic therapies. Volume expanders (fludrocortisone and desmopressin) should be used with caution. Drugs that enhance residual sympathetic tone (pyridostigmine and atomoxetine) are more effective in patients with mild disease and in MSA patients with spared postganglionic fibers. Norepinephrine replacement therapy (midodrine and droxidopa) is more effective in patients with neurodegeneration of peripheral noradrenergic fibers like PAF. NOH is often associated with other cardiovascular diseases, most notably supine hypertension, and treatment should be adapted to their presence.</jats:p>
    Scopus© Citations 19  1
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    Scopus© Citations 5  2