Anti-inflammatory Effects of Topical Hypericum perforatum: A Systematic Review
Journal
Principles and Practice of Clinical Research Journal
ISSN
2378-1890
Date Issued
2023
Author(s)
Monica Estrada
Ruth E. Chávez-Nomberto
André Saul Crestani
Ana Paula Tsuneto
Carlos Takahiro Chone
Danieli Kimura
Devy Quiroz
Erivelton de Azevedo Lopes
Habiba Ibrahim Abdullah
Jacob Eli García Torres
Joaquín Díaz-Schmidt
Levi Higino Jales Neto
Luís Fernando López
Maria Bazan
Matteo Guidetti
Piero Larco-Castilla
Santiago Sucre
Sekinah Bola-Oyebamiji
Jimena Vizarreta Rosas
Alessandra Carvalho
Type
Resource Types::text::journal::journal article
Abstract
Many inflammatory conditions directly impact the skin through different pathways, the understanding of which should be a priority to develop new medications to treat patients suffering from these conditions. Some studies have demonstrated the anti-inflammatory properties of Hypericum perforatum (HP), but no previous systematic reviews have described all the mechanisms by which topical HP may act on inflammation. Therefore, the purpose of this review was to assess the effects of topical HP on inflammatory markers in inflammatory skin conditions or models involving epithelial cells that have been described so far.