Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells

Journal
Gene
ISSN
0378-1119
Date Issued
2022
Author(s)
Fernanda Morales
Paola Pérez
Julio C. Tapia
Lorena Lobos-González
José Manuel Herranz
Francisca Guevara
Pamela Rojas de Santiago
Esteban Palacios
Rodrigo Andaur
Eduardo A. Sagredo
Katherine Marcelain
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85124163708
WoS ID
WOS:000755542300001
DOI
URL
URL Institutional Repository
Cite this document
Morales, F., Pérez, P., Tapia, J. C., Lobos-González, L., Herranz, J. M., Guevara, F., De Santiago, P. R., Palacios, E., Andaur, R., Sagredo, E. A., Marcelain, K., & Armisén, R. (2022). Increase in ADAR1p110 activates the canonical Wnt signaling pathway associated with aggressive phenotype in triple negative breast cancer cells. Gene, 819, 146246. https://doi.org/10.1016/j.gene.2022.146246
Subjects
adar1

; 

tnbc

; 

canonical wnt pathway

; 

cell invasion

; 

breast cancer

; 

adenosine deaminase

; 

animals

; 

beta catenin

; 

cell line, tumor

; 

cell movement

; 

female

; 

gene expression regulation, neoplastic

; 

glycogen synthase kinase 3 beta

; 

humans

; 

mice

; 

mice, inbred balb c

; 

phenotype

; 

rna-binding proteins

; 

triple negative breast neoplasms

; 

wnt signaling pathway

; 

adar1 protein

; 

adenosine deaminase

; 

baculoviral iap repeat containing protein 5

; 

beta catenin

; 

glycogen synthase kinase 3beta

; 

platelet endothelial cell adhesion molecule 1

; 

unclassified drug

; 

wnt protein

; 

adar protein, human

; 

adenosine deaminase

; 

beta catenin

; 

glycogen synthase kinase 3beta

; 

rna binding protein

; 

animal experiment

; 

animal model

; 

animal tissue

; 

article

; 

cancer growth

; 

canonical wnt signaling

; 

cell invasion assay

; 

controlled study

; 

human

; 

human cell

; 

immunohistochemistry

; 

in vitro study

; 

in vivo study

; 

luciferase assay

; 

mda-mb-231 cell line

; 

mouse

; 

nonhuman

; 

phenotype

; 

protein determination

; 

protein expression

; 

protein function

; 

protein protein interaction

; 

triple negative breast cancer

; 

tumor vascularization

; 

upregulation

; 

vascular endothelial cell

; 

western blotting

; 

animal

; 

bagg albino mouse

; 

cell motion

; 

female

; 

gene expression regulation

; 

genetics

; 

metabolism

; 

phenotype

; 

triple negative breast cancer

; 

tumor cell line

; 

wnt signaling