A 19 Year Analysis of Small Mammals Associated with Human Hantavirus Cases in Chile

Journal
Viruses
ISSN
1999-4915
Date Issued
2019
Author(s)
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85072585446
WoS ID
WOS:000487962400011
DOI
URL
URL Institutional Repository
Abstract
<jats:p>Small mammals present in areas where hantavirus cardiopulmonary syndrome (HCPS) cases had occurred in central and southern Chile were captured and analyzed to evaluate the abundance of rodents and seroprevalence rates of antibodies to Andes orthohantavirus (ANDV). Sampling areas ranged from the Coquimbo to Aysén regions (30–45° S approx.) regions. Ninety-two sites in peridomestic and countryside areas were evaluated in 19 years of sampling. An antibody against ANDV was detected by strip immunoassay in 58 of 1847 specimens captured using Sherman traps. Of the eleven species of rodents sampled, Abrothrix olivacea, Oligoryzomys longicaudatus and Abrothrix hirta were the most frequently trapped. O. longicaudatus had the highest seropositivity rate, and by logistic regression analysis, O. longicaudatus of at least 60 g had 80% or higher probability to be seropositive. Sex, age and wounds were significantly related to seropositivity only for O. longicaudatus. Across administrative regions, the highest seropositivity was found in the El Maule region (34.8–36.2° S), and the highest number of HCPS cases was registered in the Aysén region. Our results highlight the importance of long term and geographically extended studies, particularly for highly fluctuating pathogens and their reservoirs, to understand the implications of the dynamics and transmission of zoonotic diseases in human populations.</jats:p>
Cite this document
Torres-Pérez, F., Palma, R. E., Boric-Bargetto, D., Vial, C., Ferrés, M., Vial, P. A., Martínez-Valdebenito, C., Pavletic, C., Parra, A., Marquet, P. A., & Mertz, G. J. (2019). A 19 year analysis of small mammals associated with human hantavirus cases in chile. Viruses, 11(9), 848. https://doi.org/10.3390/v11090848
Project(s)
Subjects
andes orthohantavirus

; 

chile

; 

hantavirus cardiopulmonary syndrome

; 

hantavirus spatial distribution

; 

oligoryzomys longicaudatus

; 

peridomestic

; 

rodent reservoir

; 

seroprevalence

; 

animal distribution

; 

animals

; 

antibodies, viral

; 

chile

; 

disease reservoirs

; 

female

; 

geography

; 

hantavirus

; 

hantavirus infections

; 

hantavirus pulmonary syndrome

; 

humans

; 

male

; 

rodent diseases

; 

rodentia

; 

seroepidemiologic studies

; 

zoonoses

; 

virus antibody

; 

abrothrix hirta

; 

abrothrix longipilis

; 

abrothrix manni

; 

abrothrix olivacea

; 

abrothrix sanborni

; 

adult

; 

age distribution

; 

andes virus

; 

antibody detection

; 

article

; 

chile

; 

disease transmission

; 

female

; 

geography

; 

hantavirus infection

; 

immunoassay

; 

juvenile animal

; 

loxodontomys micropus

; 

male

; 

molecular epidemiology

; 

mus musculus

; 

nonhuman

; 

oligoryzomys longicaudatus

; 

phyllotis darwini

; 

population abundance

; 

rattus norvegicus

; 

rattus rattus

; 

sex difference

; 

small mammal

; 

wound

; 

animal

; 

animal dispersal

; 

blood

; 

chile

; 

disease carrier

; 

hantavirus

; 

hantavirus infection

; 

hantavirus pulmonary syndrome

; 

human

; 

rodent

; 

rodent disease

; 

seroepidemiology

; 

veterinary medicine

; 

virology

; 

zoonosis