Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria

Journal
Nature Communications
ISSN
2041-1723
Date Issued
2023
Author(s)
Andrés D. Klein
Tiago Fleming Outeiro
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85173824870
WoS ID
WOS:001099083700016
DOI
URL
URL Institutional Repository
Cite this document
Klein, A. D., & Outeiro, T. F. (2023). Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria. Nature Communications, 14(1), 6383. https://doi.org/10.1038/s41467-023-42107-7
Project(s)
Subjects
gaucher disease

; 

glucosylceramidase

; 

humans

; 

lysosomes

; 

mitochondria

; 

mutation

; 

glucosylceramidase

; 

mitochondrial protein

; 

reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone)

; 

glucosylceramidase

; 

energy metabolism

; 

gaucher disease

; 

gene mutation

; 

genetic variability

; 

human

; 

lysosome

; 

mitochondrion

; 

nonhuman

; 

note

; 

parkinson disease

; 

gaucher disease

; 

genetics

; 

lysosome

; 

mitochondrion

; 

mutation