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  4. Venous Air Microembolism in Chest CT Angiography: Evidence of Normalization of Deviance Phenomenon
Details

Venous Air Microembolism in Chest CT Angiography: Evidence of Normalization of Deviance Phenomenon

Journal
Indian Journal of Radiology and Imaging
ISSN
0971-3026
1998-3808
Date Issued
2021
Author(s)
SILVA FUENTE ALBA, CLAUDIO SERGIO  
Facultad de Medicina Clínica Alemana Universidad del Desarrollo  
Ema Leal
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85123293756
WoS ID
WOS:000740835400002
DOI
10.1055/s-0041-1741093
URL
https://investigadores.udd.cl/handle/123456789/4856
URL Institutional Repository
https://repositorio.udd.cl/handle/11447/7231
Abstract
<jats:title>Abstract</jats:title><jats:p>
Purpose This article provides evidence that detection of venous air microbubbles (VAMB) in chest computed tomography angiography (CTA) can be an indicator for “normalization of deviance” phenomenon in CT.</jats:p><jats:p>
Method and Materials Institutional review board-approved retrospective study, with waiver for informed consent. Contrast-enhanced chest CT performed during 6 months were reviewed for presence of VAMB in venous segments visible in chest CT (subclavian, brachiocephalic vein, superior vena cava) and cardiac chambers. VAMB volumes were quantified through a semiautomatic method (MIAlite plugin for OsiriX), using a region of interest (ROI) covering the bubble. With basal results, protocols for correct injection technique were reinforced, and VAMB were estimated again at 1 and 3 months. Six months later, questionnaires were sent to the CT technologists to inquire about their perception of VAMB. Descriptive measures with central distribution and dispersion were performed; statistical significance was considered at p < 0.05.</jats:p><jats:p>
Results A total of 602 chest CTA were analyzed, 332 were women (55.14%), with a median age of 58 (interquartile range [IQR] 44–72) years. Among those, 16.11% (100 cases) presented VAMB. Most were emergency department patients (51.6%), male (50.3%), with a median age of 54 (IQR 26) years. There was no difference on detection of VAMB regarding sex (p = 0.19), age (p = 0.46), or referral diagnosis (p = 0.35). Mean air bubbles volume was 0.2 mL (range 0.01–3.4 mL). After intervention, the number of exams with VAMB dropped to 3.29 % (3/91) (p < 0.001). On the 6-month query, 50% of the technicians still considered that VMAB is inevitable, and 60% thought that the occurrence is not associated to risk, and therefore, not actionable.</jats:p><jats:p>
Conclusion VAMB are a frequent finding in chest CTA, and being independent from patient-related variables, it is likely due to technical issues such as intravenous access manipulation during the exam. Reduction after reinforcement of proper performance, and certification of a low concern from CT technicians for any risk associated, provides evidence that there is normalization of deviance in this everyday procedure.</jats:p>
Subjects
air bubbles

; 

air embolism

; 

computed tomography angiography

; 

normalization of deviance

; 

adult

; 

aged

; 

air embolism

; 

article

; 

brachiocephalic vein

; 

computed tomographic angiography

; 

contrast enhancement

; 

dispersion

; 

emergency ward

; 

female

; 

human

; 

informed consent

; 

institutional review

; 

major clinical study

; 

male

; 

microbubble

; 

microembolism

; 

perception

; 

questionnaire

; 

retrospective study

; 

subclavian vein

; 

superior cava vein

; 

thorax radiography

; 

vein embolism

; 

venous air microbubble
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