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  4. c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling
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c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling

Journal
Scientific Reports
ISSN
2045-2322
Date Issued
2019
Author(s)
C. A. Escudero
C. Cabeza
G. Moya-Alvarado
M. T. Maloney
C. M. Flores
C. Wu
F. A. Court
W. C. Mobley
F. C. Bronfman
Carolina Cabeza
Facultad de Medicina Clínica Alemana Universidad del Desarrollo  
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85064445045
WoS ID
WOS:000464495700018
DOI
10.1038/s41598-019-42420-6
URL
https://investigadores.udd.cl/handle/123456789/2467
URL Institutional Repository
http://hdl.handle.net/11447/6324
Cite this document
Escudero, C. A., Cabeza, C., Moya-Alvarado, G., Maloney, M. T., Flores, C. M., Wu, C., Court, F. A., Mobley, W. C., & Bronfman, F. C. (2019). C-jun n-terminal kinase (Jnk)-dependent internalization and rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal bdnf-p75 signaling. Scientific Reports, 9(1), 6070. https://doi.org/10.1038/s41598-019-42420-6
Subjects
p75 neurotrophin receptor

; 

nuclear translocation

; 

transport

; 

survival

; 

growth

; 

jnk

; 

inhibitor

; 

trka

; 

nrif

; 

localization

; 

animals

; 

apoptosis

; 

axons

; 

brain-derived neurotrophic factor

; 

cells, cultured

; 

endosomes

; 

female

; 

jnk mitogen-activated protein kinases

; 

male

; 

nerve tissue proteins

; 

neurons

; 

primary cell culture

; 

rab5 gtp-binding proteins

; 

rats

; 

receptor, trka

; 

receptors, growth factor

; 

superior cervical ganglion

; 

bdnf protein, rat

; 

brain derived neurotrophic factor

; 

growth factor receptor

; 

nerve protein

; 

ngfr protein, rat

; 

protein tyrosine kinase a

; 

rab protein

; 

stress activated protein kinase

; 

animal

; 

apoptosis

; 

axon

; 

cell culture

; 

cytology

; 

drug effect

; 

endosome

; 

female

; 

male

; 

metabolism

; 

nerve cell

; 

pathology

; 

primary cell culture

; 

rat

; 

superior cervical ganglion
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