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  4. Clinical, immunologic, and genetic characteristics of 148 patients with natural killer cell deficiency
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Clinical, immunologic, and genetic characteristics of 148 patients with natural killer cell deficiency

Journal
Journal of Allergy and Clinical Immunology
ISSN
0091-6749
Date Issued
2025-05
Author(s)
Manar Abdalgani
Evelyn R. Hernandez
Luis A. Pedroza
Ivan K. Chinn
Lisa R. Forbes Satter
Nicholas L. Rider
Pinaki P. Banerjee
POLI HARLOWE, MARIA CECILIA BERTA  
Facultad de Medicina Clínica Alemana Universidad del Desarrollo  
Sanjana Mahapatra
Debra Canter
Tram Cao
Linda M. Shawver
Sarada L. Nandiwada
James R. Lupski
Jennifer E. Posey
Rajasekhar Ramakrishnan
Emily M. Mace
Jordan S. Orange
Type
journal-article
DOI
10.1016/j.jaci.2025.01.030
URL
https://investigadores.udd.cl/handle/123456789/11066
Subjects
adolescent

; 

adult

; 

aged

; 

child

; 

child

; 

preschool

; 

exome sequencing

; 

female

; 

humans

; 

immunologic deficiency syndromes

; 

infant

; 

infant

; 

newborn

; 

killer cells

; 

natural

; 

male

; 

middle aged

; 

young adult

; 

interferon consensus sequence binding protein

; 

protein cdc42

; 

ras related protein rab 27a

; 

transcription factor gata 2

; 

abscess

; 

actb gene

; 

adolescent

; 

article

; 

bronchiectasis

; 

candidiasis

; 

case fatality rate

; 

cdc45 gene

; 

cell function

; 

cells by body anatomy

; 

child

; 

clinical feature

; 

clinical practice

; 

cohort analysis

; 

controlled study

; 

cytomegalovirus infection

; 

cytopenia

; 

cytotoxicity

; 

dock8 gene

; 

elf4 gene

; 

epstein barr virus infection

; 

esophagitis

; 

fcgr3a gene

; 

female

; 

gastrointestinal infection

; 

gata2 deficiency

; 

gene

; 

genetic association

; 

genetic trait

; 

genital herpes

; 

gins4 gene

; 

hematologic malignancy

; 

hematopoietic stem cell transplantation

; 

hemophagocytic syndrome

; 

hepatitis

; 

hepatosplenomegaly

; 

herpes labialis

; 

herpes simplex

; 

herpes virus infection

; 

herpes zoster

; 

herpetic gingivostomatitis

; 

hodgkin disease

; 

human

; 

immunological parameters

; 

immunophenotyping

; 

infant

; 

inflammatory bowel disease

; 

major clinical study

; 

male

; 

mcm10 gene

; 

medical research

; 

myocarditis

; 

natural killer cell

; 

natural killer cell count

; 

neurologic disease

; 

newborn

; 

nfat5 gene

; 

nfkb2 gene

; 

nlrp4 gene

; 

observational study

; 

otitis media

; 

papillomavirus infection

; 

pik3cd gene

; 

plcg2 gene

; 

pneumonia

; 

pomp gene

; 

recurrent infection

; 

sinusitis

; 

skin abscess

; 

skin infection

; 

skin lymphoma

; 

soft tissue abscess

; 

t cell lymphoma

; 

thyroid disease

; 

ttc7a gene

; 

upper respiratory tract infection

; 

viremia

; 

wart

; 

whole exome sequencing

; 

zbtb24 gene

; 

genetics

; 

immune deficiency

; 

immunology

; 

middle aged

; 

natural killer cell

; 

preschool child

; 

cytotoxicity, immunogenetics

; 

gene pathogenic alleles

; 

herpesvirus

; 

inborn errors of immunity

; 

nk cells

; 

primary immunodeficiency
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