Chaperone Mediated Autophagy Degrades TDP-43 Protein and Is Affected by TDP-43 Aggregation

Journal
Frontiers in Molecular Neuroscience
ISSN
1662-5099
Date Issued
2020
Author(s)
Fernando Ormeño
José Moreno
Felipe Riquelme
Javiera Rios
Alfredo Criollo
Amelina Albornoz
Mauricio Budini
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85080881119
WoS ID
WOS:000518609100001
DOI
URL
URL Institutional Repository
Cite this document
Ormeño, F., Hormazabal, J., Moreno, J., Riquelme, F., Rios, J., Criollo, A., Albornoz, A., Alfaro, I. E., & Budini, M. (2020). Chaperone mediated autophagy degrades tdp-43 protein and is affected by tdp-43 aggregation. Frontiers in Molecular Neuroscience, 13, 19. https://doi.org/10.3389/fnmol.2020.00019
Subjects
tardbp

; 

protein aggregation

; 

cellular model

; 

chaperone mediated autophagy

; 

lysosomal damage

; 

amyotrophic lateral sclerosis

; 

heat shock cognate protein 70

; 

lysosome associated membrane protein 2

; 

tar dna binding protein

; 

tar dna binding protein 43 kda

; 

unclassified drug

; 

amyotrophic lateral sclerosis

; 

animal tissue

; 

article

; 

cell activity

; 

cell damage

; 

cell isolation

; 

chaperone-mediated autophagy

; 

controlled study

; 

down regulation

; 

embryo

; 

enzyme inhibition

; 

enzyme substrate

; 

hek293 cell line

; 

human

; 

human cell

; 

in vivo study

; 

liver cell culture

; 

lysosome membrane

; 

male

; 

neuropathology

; 

nonhuman

; 

protein aggregation

; 

protein degradation

; 

protein expression level

; 

protein homeostasis

; 

protein localization

; 

protein protein interaction

; 

rat

; 

upregulation

; 

wild type