Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells

Journal
Biochemical Pharmacology
ISSN
0006-2952
Date Issued
2020
Author(s)
Rina Ortiz
Jorge Díaz
Natalia Díaz-Valdivia
Samuel Martínez
Layla Simón
Pamela Contreras
Lorena González-sánchez
Simón Guerrero
Lisette Leyton
Andrew F.G. Quest
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85083288571
WoS ID
WOS:000541248000017
DOI
URL
URL Institutional Repository
Cite this document
Ortiz, R., Díaz, J., Díaz-Valdivia, N., Martínez, S., Simón, L., Contreras, P., Lobos-González, L., Guerrero, S., Leyton, L., & Quest, A. F. G. (2020). Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells. Biochemical Pharmacology, 177, 113941. https://doi.org/10.1016/j.bcp.2020.113941
Subjects
melanoma

; 

metastasis

; 

migration

; 

phospho-caveolin-1

; 

src-family kinase inhibitors

; 

animals

; 

caveolin 1

; 

cell line, tumor

; 

cell movement

; 

cell survival

; 

dasatinib

; 

female

; 

lung neoplasms

; 

male

; 

melanoma, experimental

; 

mice

; 

mice, inbred c57bl

; 

neuropeptides

; 

phosphorylation

; 

protein kinase inhibitors

; 

pyrimidines

; 

rac1 gtp-binding protein

; 

skin neoplasms

; 

src-family kinases

; 

transfection

; 

tyrosine

; 

4 amino 7 tert butyl 5 (4 chlorophenyl)pyrazolo[3,4 d]pyrimidine

; 

abelson kinase

; 

caveolin 1

; 

dasatinib

; 

gelatinase a

; 

gelatinase b

; 

protein tyrosine kinase

; 

rac1 protein

; 

4 amino 7 tert butyl 5 (4 chlorophenyl)pyrazolo[3,4 d]pyrimidine

; 

cav1 protein, mouse

; 

caveolin 1

; 

dasatinib

; 

neuropeptide

; 

protein kinase inhibitor

; 

protein tyrosine kinase

; 

pyrimidine derivative

; 

rac1 protein

; 

rac1 protein, mouse

; 

tyrosine

; 

animal cell

; 

animal experiment

; 

animal model

; 

animal tissue

; 

article

; 

cell migration

; 

controlled study

; 

enzyme activation

; 

enzyme activity

; 

in vitro study

; 

in vivo study

; 

lung metastasis

; 

melanoma cell

; 

metastasis inhibition

; 

metastasis potential

; 

metastatic melanoma

; 

mouse

; 

nonhuman

; 

priority journal

; 

protein phosphorylation

; 

animal

; 

c57bl mouse

; 

cell motion

; 

cell survival

; 

drug effect

; 

experimental melanoma

; 

female

; 

genetic transfection

; 

genetics

; 

lung tumor

; 

male

; 

metabolism

; 

pathology

; 

phosphorylation

; 

skin tumor

; 

tumor cell line