Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood–brain barrier function
Journal
Molecular Psychiatry
ISSN
1359-4184
1476-5578
Date Issued
2022
Author(s)
Bárbara S. Casas
Gabriela Vitória
Catalina P. Prieto
Mariana Casas
Carlos Chacón
Markus Uhrig
Stevens K. Rehen
Verónica Palma
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Cite this document
Casas, B. S., Vitória, G., Prieto, C. P., Casas, M., Chacón, C., Uhrig, M., Ezquer, F., Ezquer, M., Rehen, S. K., & Palma, V. (2022). Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood–brain barrier function. Molecular Psychiatry, 27(9), 3708-3718. https://doi.org/10.1038/s41380-022-01653-0
Subjects
growth-factor
;
matrix-metalloproteinase-9 mmp-9
;
neurotrophic factor
;
gene
;
polymorphism
;
expression
;
insights
;
hypoxia
;
pathway
;
risk
;
animals
;
blood-brain barrier
;
brain
;
cell line
;
humans
;
induced pluripotent stem cells
;
mice
;
schizophrenia
;
tight junction protein
;
angiogenesis
;
animal cell
;
animal experiment
;
article
;
blood brain barrier
;
brain cell
;
capillary endothelial cell
;
cell function
;
controlled study
;
disease association
;
gene
;
hcmec/d3 cell line
;
immunofluorescence
;
in vitro study
;
in vivo study
;
induced pluripotent stem cell
;
male
;
molecular interaction
;
mouse
;
nonhuman
;
protein expression
;
schizophrenia
;
transcriptomics
;
animal
;
blood brain barrier
;
brain
;
cell line
;
human
;
metabolism