MUÑOZ VENTURELLI, PAULA ANDREA
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MUÑOZ VENTURELLI, PAULA ANDREA
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paumunoz@udd.cl
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56071369200

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2024 2024 2023 2023 2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 2016 2016 2015 2015 0.0 0.0 0.5 0.5 1.0 1.0 1.5 1.5 2.0 2.0 2.5 2.5 3.0 3.0 3.5 3.5 4.0 4.0

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Disparities in Stroke Incidence Over Time by Sex and Age in Latin America and the Caribbean Region 1997 to 2021: A Systematic Review and Meta‐Analysis

2023 , Marilaura Nuñez , Carlos Delfino , Claudia Asenjo‐Lobos , SCHILLING REDLICH, ANDREA INGRID , LAVADOS GERMAIN, PABLO MANUEL , Craig S. Anderson , MUÑOZ VENTURELLI, PAULA ANDREA

Background High‐income country studies show unfavorable trends in stroke incidence (SI) in younger populations. We aimed to estimate temporal change in SI disaggregated by age and sex in Latin America and the Caribbean region. Methods and Results A search strategy was used in MEDLINE, WOS, and LILACS databases from 1997 to 2021, including prospective population‐based observational studies with first‐ever stroke incidence in Latin America. Reports without data broken down by age and sex were excluded. Risk of bias was assessed with The Joanna Briggs Institute's guide. The main outcomes were incidence rate ratio and relative temporal trend ratio of SI, comparing time periods before 2010 with after 2010. Pooled relative temporal trend ratios considering only studies with 2 periods in the same population were calculated by random‐effects meta‐analysis. Meta‐regression analysis was used to evaluate incidence rate determinants. From 9242 records identified, 6 studies were selected including 4483 first‐ever stroke in 4 101 084 individuals. Crude incidence rate ratio in younger subjects (<55 years) comparing before 2010:after 2010 periods showed an increase in SI in the past decade (incidence rate ratio, 1.37 [95% CI, 1.23–1.50]), in contrast to a decrease in older people during the same period (incidence rate ratio, 0.83 [95% CI, 0.76–0.89]). Overall relative temporal trend ratio (<55:≥55 years) was 1.65 (95 CI%, 1.50–1.80), with higher increase in young women (pooled relative temporal trend ratio, 3.08 [95% CI, 1.18–4.97]; P for heterogeneity <0.001). Conclusions An unfavorable change in SI in young people, especially in women, was detected in population‐based studies in the past decade in Latin America and the Caribbean. Further investigation of the explanatory variables is required to ameliorate stroke prevention and inform local decision‐makers. Registration URL: https://www.crd.york.ac.uk/prospero/ Identifier: CRD42022332563.

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Implementation of Low-Intensity Thrombolysis Monitoring Care in Routine Practice: Process Evaluation of the Optimal Post rtPA-IV Monitoring in Acute Ischemic Stroke Study in the USA

2024 , Menglu Ouyang , Francisca González , Michelle Montalbano , April Pruski , Stephen Jan , Xia Wang , Brenda Johnson , Debbie V. Summers , Pooja Khatri , Alejandra Malavera , Michael Iacobelli , Roland Faigle , MUÑOZ VENTURELLI, PAULA ANDREA , Francisca Urrutia Goldsack , Diana Day , Thompson G. Robinson , Alice C. Durham , Ahtasam Ebraimo , Lili Song , Yi Sui , Wan Asyraf Wan Zaidi , Richard I. Lindley , Candice Delcourt , Victor Cruz Urrutia , Craig S. Anderson , Hueiming Liu

<b><i>Introduction:</i></b> The ongoing OPTIMISTmain study, an international, multicenter, stepped-wedge cluster randomized trial, aims to determine effectiveness and safety of low-intensity versus standard monitoring in thrombolysis-treated patients with mild-to-moderate acute ischemic stroke (AIS). An embedded process evaluation explored integration and impact of the intervention on care processes at participating US sites. <b><i>Methods:</i></b> A mixed-methods approach with quantitative and qualitative data was collected between September 2021 and November 2022. Implementer surveys were undertaken at pre- and post-intervention phases to understand the perceptions of low-intensity monitoring strategy. A sample of stroke care nurses were invited to participate in semi-structured interviews at an early stage of post-intervention. Qualitative data were analyzed deductively using the normalization process theory; quantitative data were tabulated. <b><i>Results:</i></b> Interviews with 21 nurses at 8 hospitals have shown low-intensity monitoring was well accepted as there were less time constraints and reduced workload for each patient. There were initial safety concerns over missing deteriorating patients and difficulties in changing established routines. Proper training, education, and communication, and changing the habits and culture of care, were key elements to successfully adopting the new monitoring care into routine practice. Similar results were found in the post-intervention survey (42 nurses from 13 hospitals). Nurses reported time being freed up to provide patient education (56%), daily living care (50%), early mobilization (26%), mood/cognition assessment (44%), and other aspects (i.e., communication, family support). <b><i>Conclusions:</i></b> Low-intensity monitoring for patients with mild-to-moderate AIS, facilitated by appropriate education and organizational support, appears feasible and acceptable at US hospitals.

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Acute Treatment of Stroke (Except Thrombectomy)

2018 , MUÑOZ VENTURELLI, PAULA ANDREA , Jason P. Appleton , Craig S. Anderson , Philip M. Bath

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Influence of Including Patients with Premorbid Disability in Acute Stroke Trials: The HeadPoST Experience

2021 , Xia Wang , Tom J. Moullaali , Menglu Ouyang , Laurent Billot , Else Charlotte Sandset , Lili Song , Candice Delcourt , Maree L. Hackett , Caroline L. Watkins , Thompson G. Robinson , Jie Yang , LAVADOS GERMAIN, PABLO MANUEL , BRUNSER, ALEJANDRO , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , MUÑOZ VENTURELLI, PAULA ANDREA , Hisatomi Arima , Sandy Middleton , Octávio M. Pontes-Neto , Jeyaraj Durai Pandian , Kris Rogers , Craig S. Anderson

<b><i>Background:</i></b> Patients with premorbid functional impairment are generally excluded from acute stroke trials. We aimed to determine the impact of including such patients in the Head Positioning in acute Stroke Trial (HeadPoST) and early additional impairment on outcomes. <b><i>Methods:</i></b> Post hoc analyses of HeadPoST, an international, cluster-randomized crossover trial of lying-flat versus sitting-up head positioning in acute stroke. Associations of early additional impairment, defined as change in modified Rankin scale (mRS) scores from premorbid levels (estimated at baseline) to Day 7 (“early ΔmRS”), and poor outcome (mRS score 3–6) at Day 90 were determined with generalized linear mixed model. Heterogeneity of the trial treatment effect was tested according to premorbid mRS scores 0–1 versus 2–5. <b><i>Results:</i></b> Of 8,285 patients (38.9% female, mean age 68 ± 13 years) with complete data, there were 1,984 (23.9%) with premorbid functional impairment (mRS 2–5). A significant linear association was evident for early ∆mRS and poor outcome (per 1-point increase in ΔmRS, adjusted odds ratio 1.20, 95% confidence interval 1.14–1.27; <i>p</i> &#x3c; 0.0001). Patients with greater premorbid functional impairment were less likely to develop additional impairment, but their risk of poor 90-day outcome significantly increased with increasing (worse) premorbid mRS scores (linear trend <i>p</i> &#x3c; 0.0001). There was no heterogeneity of the trial treatment effect by level of premorbid function. <b><i>Conclusions:</i></b> Early poststroke functional impairment that exceeded premorbid levels was associated with worse 90-day outcome, and this association increased with greater premorbid functional impairment. Yet, including premorbid impaired patients in the HeadPoST did not materially affect the subsequent treatment effect. <b><i>Clinical Trial Registration:</i></b> HeadPoST is registered at http://www.ClinicalTrials.gov (NCT02162017).

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Intensive Care Unit Admission for Patients in the INTERACT2 ICH Blood Pressure Treatment Trial: Characteristics, Predictors, and Outcomes

2017 , Katja E. Wartenberg , Xia Wang , MUÑOZ VENTURELLI, PAULA ANDREA , Alejandro A. Rabinstein , LAVADOS GERMAIN, PABLO MANUEL , Craig S. Anderson , Thompson Robinson

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Quantifying regional variations in components of acute stroke unit (ASU) care in the international HeadPoST study

2020 , Menglu Ouyang , Yao Zhang , Xia Wang , Lili Song , Laurent Billot , Thompson Robinson , LAVADOS GERMAIN, PABLO MANUEL , Hisatomi Arima , Maree L. Hackett , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , MUÑOZ VENTURELLI, PAULA ANDREA , Sandy Middleton , Caroline L. Watkins , Octavio M. Pontes-Neto , Tsong-Hai Lee , BRUNSER, ALEJANDRO , Craig S. Anderson

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The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): an international, stepped wedge cluster randomised controlled trial

2023 , Lu Ma , Xin Hu , Lili Song , Xiaoying Chen , Menglu Ouyang , Laurent Billot , Qiang Li , Alejandra Malavera , Xi Li , Paula Muñoz-Venturelli , Asita de Silva , Nguyen Huy Thang , Kolawole W Wahab , Jeyaraj D Pandian , Mohammad Wasay , Octavio M Pontes-Neto , Carlos Abanto , Antonio Arauz , Haiping Shi , Guanghai Tang , Sheng Zhu , Xiaochun She , Leibo Liu , Yuki Sakamoto , Shoujiang You , Qiao Han , Bernard Crutzen , Emily Cheung , Yunke Li , Xia Wang , Chen Chen , Feifeng Liu , Yang Zhao , Hao Li , Yi Liu , Yan Jiang , Lei Chen , Bo Wu , Ming Liu , Jianguo Xu , Chao You , Craig S Anderson , Thompson Robinson , J. Jaime Miranda , Craig S. Anderson , Chao You , Lili Song , Adrian Parry-Jones , Nikola Sprigg , Sophie Durrans , Caroline Harris , Ann Bamford , Olivia Smith , Robert Herbert , Christopher Chen , William Whiteley , Rong Hu , Laurent Billot , Qiang Li , Jayanthi Mysore , Xin Hu , Yao Zhang , Feifeng Liu , Yuki Sakamoto , Shoujiang You , Qiao Han , Bernard Crutzen , Yunke Li , Emily Cheung , Stephen Jan , Hueiming Liu , Menglu Ouyang , Lingli Sun , Honglin Chu , Anila Anjum , Francisca Gonzalez Mc Cawley , Alejandra Del Rio , Bruna Rimoli , Rodrigo Cerantola , Thanushanthan Jeevarajah , Madhushani Kannangara , Andrene Joseph , Chamath Nanayakkara , Xiaoying Chen , Alejandra Malavera , Chunmiao Zhang , Zhao Yang , Brook Li , Zhuo Meng , Menglu Ouyang , Leibo Liu , Yi Ning , Le Dong , Manuela Armenis , Joyce Lim , Helen Monaghan , Lu Ma , Xin Hu , Xi Li , Rui Luo , Guojuan Cheng , Yilin Dong , Ziqin Liu , Shuihong Wang , Ying Zhang , Jipeng Cheng , Hui Shi , Wenjing Li , Langming Mou , Ping Yi , Chen Chen , Xue Chen , Shalomi Weerawardena , Poornima Ellawala , Enalee Ranasinghe , Chrishmi Rodrigo , Kolawala Wahab , Sunday Adeniyi , Jeyaraj Pandian , Megha Khanna , MUÑOZ VENTURELLI, PAULA ANDREA , RECULE GONZALEZ, FRANCISCA , Francisca Urrutia Goldsack , Mohammad Wasay , Dilshad Begum , Anila Anjum , Octavio Pontes-Neto , Millene Camilo , Francisco Dias , Octavio Vincenzi , Rodrigo Cerantola , Carla Moro , Renata Santos , Nara Texeira , Alexandre Longo , Rafaela Liberato , Sheila Martins , Arthur Pille , Bruna Chwal , Isabel Silva , Natacha Titton , Gustavo Weiss , Daissy Mora , Magda Ouriques , Leonardo Carbonera , Rodrigo Bazan , Gabriel Modolo , Fernanda Winckler , Luana Miranda , Juli Souza , Alexis Rojo , Wilhelm Uslar , Lorena Medel , Javiera Lopez , Diego Herrero , LAVADOS GERMAIN, PABLO MANUEL , Barbara Vargas Latorre , Nathalie Conejan , Tomas Esparza , Patricio Sotomayor , Denisse Wenger , Juan Pablo Gigoux , Aldo Letelier , Lilian Acevedo , Vivianne Moya , Cristian Figueroa , Nicol Vallejos , Nathalie Conejan , Tomas Esparza , Patricio Sotomayor , Rodrigo Guerrero , Mauricio Velasquez , Jose Vallejos , Kimerly Pallauta , Tamara Santibanez , Angelo Queirolo , Andrea Lobos , Yongming Jiang , Weimin Li , Wei Huang , Ke Luo , Gangying Liu , Guanghai Tang , Guang Yang , Hongtao Jiang , Xu Zhang , Hongyan Jing , Sheng Zhu , Bo Pu , Dong Lv , Hui Kang , Qiuping Hu , Xiaochun She , Xiaoming Jiang , Yanli Chen , Shenghua Yang , Jianjun He , Zongping Li , Gang Cheng , Hailin Huang , Xiaoyi Wang , Jianqiong Lin , Minhui Chen , Chenghao Yang , Hao Ding , Yunliang Deng , Fei Luo , Rongjun Zhang , Xiaofeng Wang , Hongbing Zhang , Xiaoliang Yang , Yang Zhang , Chengyi Yang , Yu He , Feng Liu , Rongjie Wang , Yuhui Zhang , Xiaodong Xin , Bin Feng , Wanru Hao , Chang Song , Yun Guo , Dehua Jiang , Jie Chen , Changtong Tang , Hongliang Zhu , Xin Li , Jin Cui , Haidong Xu , Boyang Li , Fusheng Tang , Yuanbin Li , Min Gao , Bo Yang , Xuejun Xu , Bing Deng , Yi Zheng , Yuanhong Ge , Keyu Chen , Yang Liu , Xinshen Li , Tingting Zhong , Jianfeng Xu , Hai Zhang , Jiyue Wang , Jianxin Zhu , Hanyu Sun , Fuhua Yu , Xueguang Zhang , Chao You , Lu Ma , Xin Hu , Jianguo Xu , Xi Li , Mingsen Zhang , Bin Wang , Yiming Ma , Donglin Jiang , Jun Zhou , Cong Liu , Wenhong Nie , Mingguo Li , Tao Tian , Yong Li , Mingfang He , Xiaolong Tu , Zhengjun Wu , Hong Liu , Dongsheng Zhong , Rongcai Jiang , Jian Sun , Ye Tian , Yingsheng Wei , Shuo An , Pingbo Wei , Le Luo , Bin Lin , Gang Liu , Yan Wen , Qiang Cai , Qianxue Chen , Pan Lei , Zhiyang Li , Meifang Zhang , Jiaquan He , Yan Chen , Jun Liu , Xinghai Liu , Junyan Li , Min Chen , Jing Wang , Bingzhi Zhou , Baichun Ye , Jiancheng Zhang , Manyuan Zhang , Xuming Pan , Xiaoxiang Yu , Jian Xu , Qingbao Xiao , Yuefei Wang , Liang Tao , Lin Shi , Niandong Zheng , Guoliang You , Bo Lei , Shu Chen , Honggang Wu , Jin Hu , Jianlan Zhao , Jian Yu , Qiang Yuan , Zhuoying Du , Xielin Tang , Qianke Li , Shenghua Liu , Feilong Yang , Kui Xiao , Chao Luo , Guang Wang , Xudong Che , Zhipeng Teng , Wenwu Wan , Jun Li , Yu Liu , Mingbo Fan , Tao Zhang , Lun Cai , Yuan Ma , Zhifeng Ma , Bin Li , Linlin He , Jinghui Li , Weibing Zhang , Shuxin Zhang , Hongzhen Zhang , Yingguang Dai , Jun Lei , Lei Mao , Yiyang Huang , Zhi Zhou , Ping Chen , Fang Chen , Pan Wei , Tiangui Li , Honglin Chen , Mengfei Zeng , Kejie Mou , Jun Xue , Yong Jiang , Xiaoping Tang , Tao Chen , Yalan Zhang , Yanbing Xu , Yuchen Gu , Lei Chen , Yujun Zhao , Bin Yang , Peng Kuai , Xi Wang , Yuwang Yang , Xueling Hu , Huitian Zhang , Yintao Yang , Weifeng Wang , Junyi Zhang , Wei Cheng , Xiaoxue Zhang , Xiaowen Ma , Qin He , Li Zhang , Rong Gao , Huixiang Liu , Jingwei Ye , Ping Xu , Xin Wu , Yuan Yuan , Peng Zou , Zhen Zhang , Jiyong Cheng , Zhangming Zhou , Yijun Zeng , Zhang Liang , Deming Du , Shui Yu , Yongjun Cao , Shoujiang You , Jiaping Xu , Zhichao Huang , Dongqin Chen , Wenfeng Xiao , Li Zhu , Miao Yuan , Yuhai Wang , Dongliang Shi , Xu Hu , Dingchao Xiang , Like Shi , Hongqin Wang , Liu Yang , Wang Miao , Yiyi Hu , Yuchun Zhao , Xi Hu , Yang Liu , Weiduo Zhou , Chao Sun , Tao Chen , Dong Tang , Kun Yao , Jin You , Shishi Chen , Jianmin Yao , Huanmei Li , Jinmei Liu , Ailin Bai , Yong Yi , Qingshan Deng , Peng Luo , Han Wang , Jingcheng Jiang , Qingwei Yang , Shunpo He , Jun Wang , Yu Chen , Hua He , Yuyang Deng , Zhikai Cao , Xuxia Yi , Jinbiao Luo , Shuang Luo , Min Gong , Li Liu , Xuejun Gao , Jia Liu , Li'e Wu , Jia Zhang , Hongying Sun , Xinhui Li , Lu Jia , Jianbing Wu , Jie Zhang , Huajun Zhang , Chunfu Du , Shun Li , Xiaobin Yang , Jie He , Lei Liao , Gezhi Zhou , Wentao Dong , Yunxiang Chen , Xiaofeng Lin , Xujian Shui , Peng Zhang , Yuan Zhao , Hongli Yang , Wenbin Zhao , Xiaoyi Zhang , Jincao Chen , Qian Wu , Xuan Dai , Baogui Tang , Yinjuan Wang , Tao Liu , Haixia Zhang , Faliang Duan , Ming Luo , Qingfang Jiao , Guoliang Lei , Dong Wang , Chunwang Song , Haopeng Tan , Feng Ye , Xinghu Qin , Xiaolong Liang , Junling Liu , Lang Yang , Jie Yang , Yapeng Lin , Qian Yang , Xuntai Ma , Yinkuang Qi , Baogen Pan , Caixia Jiang , Zhanying Ye , Ce Dong , Xiongfei Yue , Xiaopeng Yang , Tuoheti Maimaitiyiming , Jun Dong , Yonggang Wu , Feng Gao , Deqiang Zhao , Xinghai Zhang , PengJun Wang , Hongbo Jiang , Jianping Li , Wei Zhang , Jing Chen , Haibo Tong , Yonghong Wang , Kaipeng Qiao , Fuyou Guo , Mingchu Zhang , Yan Hu , Mengzhao Feng , Dengpan Song , Yi Zuo , Shangjun Chen , Chao Qian , Baoming Li , Jingku Ma , Sunfu Zhang , Bin Kong , Xingyu Dong , Qiang Li , Sheng Fang , Bin Lu , Yang Li , Zhen Zhang , Yongling Yang , Hong Yu , Huaiyu Sun , Yue Wang , Weimin Wang , Tong Li , Shengli Li , Zhiming Xu , Yongyi Wang , Qiang Dong , Yuping Tang , Heling Chu , Ying Lu , Zhong Wang , Xiaoou Sun , Jianhua Zhao , Shuaifeng Yang , Xiying Qian , Aralikatte Onkarappa Saroja , Ravishankar Naik k , Sandip Chindhi , Nakul Pampaniya , Kurubara Amaresh , Thomas Iype , Dileep R , Reeja Rajan , Praveen Panicker , Rupjyoti Das , Nupur Choudhury , Pankaja Gohain , Jemin Webster , Biyol Pakma , Lalbiak Sangi , Ivy Sebastian , Gaurav Aggrawal , Komal Raj , Deepankshi Rajoura , Sulena Singh , Varun Aggrawal , Amit Narang , Antonio Arauz , Vanesa Cano-Nigenda , Diego López-Mena , Héctor Valdez-Ruvalcaba , Roberto Toledo-Treviño , Reginald Obiako , Sani Abubakar , Oguike Emeka , Balogun Olayemi , Melika Lois , Ibinaiye Philip , Olurishe Comfort O , Njideka Okubadejo , Osigwe Agabi , Oluwadamilola Ojo , Kolawole Wahab , Abiodun Bello , Oyinloye Ibukun , Olufemi Sanayaolu , Sunday Adeniyi , Abdulraheem Jimoh , Mohammad Wasay , Dilshad Begum , Anila Anjum , Shahid Waheed , Dr.Ayeesha Kamal , Raja Farhat Shoaib , Fizza Orooj , Sadaf Majid , Taskeen Zehra , Abdus Salam Khan , Ravi Shanker , Nadir Ali Syed , Nashwa Ahmad , Carlos Abanto , Ana Valencia , Danny Barrientos , Jorge Ramirez , Pilar Calle , Dilum Palliyeguruge , Sumudu Muthucumarana , Shiroma Ratnayaka , Dilhara Ganihiarachchi , Arundathi Bandaranayake , S.D.B Somaratne , Saumya Narayana , Sithara Gallage , Bimsara Senanayake , Udari Samarasiri , Dunya Luke , Mythily Sivapathasundaram , Vithoosan Sahadevan , Amani Rasmi , Yuran Deshaka , Nilukshi Fernando , Aruna Munasinghe , Kapilanga Rathnapriya , A.S Nissanka , Kanchana Karunathilake , Isuru Gayan , Kaminda Wijenayake , Hasitha Gunasekara , Jagath Vidyarathne , Ajantha Keshavaraj , Kanagasabapathy Janarthanan , Arhivalaky Gerald Jeevathasan , Sivaram Sivamainthan , Mathyamuthan John Priyanth , Abirami John Priyanth , Thambippillai Rajendiran , Sanjeewa Alwis , Nushara Gunasekare , Vasundara Liyanarachchi , Athula Dissanayake , Wimalasiri Mewa Uluwattage , Gimhani Ratnayake , Charika Rajinee , Sakura Jayawardana , Janaka Peiris , Ranjith Wicramasinghe , Chamila Fernando , Jessie Abbas , Nethmini Withanage , Makaranda Bandara , Duy Ton Mai , Van Chi Nguyen , Viet Phuong Dao , Xuan Trung Vuong , Tien Dung Nguyen , Trung Hieu Dinh , Ha Quan Phan , Quoc Viet Bui , Dinh Tho Phung , Quang Tho Pham , Dinh Dai Pham , Duc Thuan Do , Phuc Duc Dang , Minh Duc Dang , Dang Hai Nguyen , Thi Phuong Nga Nguyen , Quoc Huy Nguyen , Quoc Dai Pham , Quoc Vinh Chau , Vinh Thy Van Tai , Tran Vinh Le , Cong Tri Le , Ha Mai Khuong Tran , Huu Khanh Nguyen , Hoang Minh Thao Ngyen , Duc Chien Vo , Thai My Phuong Nguyen , Trung Thanh Tran , Thi Hanh Vi Vo , Hao Nhien Cao , Ba Thang Nguyen , Thi Ngoc Suong Le , Thien Duc La , Chi Duc Pham , Huy Thai

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Recommendations for Implementing the INTERACT3 Care Bundle for Intracerebral Hemorrhage in Latin America: Results of a Delphi Method

2024 , Ma. Ignacia Allende , MUÑOZ VENTURELLI, PAULA ANDREA , GONZALEZ MC CAWLEY, FRANCISCA , Francisca Bascur , Craig S. Anderson , Menglu Ouyang , CABIESES VALDES, BALTICA BEATRIZ , OBACH KING, ALEXANDRA ALICE , Vanessa Cano-Nigenda , Antonio Arauz

<b><i>Introduction:</i></b> The third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3) showed that the implementation of a care bundle improves outcomes after acute intracerebral hemorrhage (ICH). We aimed to establish consensus-based recommendations for the broader integration of the care bundle across Latin American countries (LAC). <b><i>Methods:</i></b> A 3-phase Delphi study allowed a panel of 32 healthcare workers from 14 LAC to sequentially rank statements relevant to 7 domains (training, resources/infrastructure, patient education, blood pressure, temperature, glycemic control, and anticoagulation reversal). The pre-defined consensus threshold was 75%. <b><i>Results:</i></b> A total of 43 statements reached consensus by the third round, with 12 new statements emerging through rounds. The highest-ranked statements in each domain emphasized critical aspects, but successful implementation requires appropriate resourcing. Key priorities were continuous training of all healthcare workers in ICH management, establishing protocols aligned with available resources, and collaborative interdisciplinary care supported by institutional networks. Statements related to anticoagulation reversal had the highest priority. <b><i>Conclusions:</i></b> Consensus statements are provided to facilitate integration of the INTERACT3 care bundle to reduce disparities in ICH outcomes in LAC.

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Low blood pressure and adverse outcomes in acute stroke: HeadPoST study explanations

2020 , Menglu Ouyang , MUÑOZ VENTURELLI, PAULA ANDREA , Laurent Billot , Xia Wang , Lili Song , Hisatomi Arima , LAVADOS GERMAIN, PABLO MANUEL , Maree L. Hackett , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , BRUNSER, ALEJANDRO , Sandy Middleton , Octavio M. Pontes-Neto , Tsong-Hai Lee , Caroline L. Watkins , Thompson Robinson , Craig S. Anderson

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Cluster-Randomized, Crossover Trial of Head Positioning in Acute Stroke

2017 , Craig S. Anderson , Hisatomi Arima , LAVADOS GERMAIN, PABLO MANUEL , Laurent Billot , Maree L. Hackett , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , MUÑOZ VENTURELLI, PAULA ANDREA , BRUNSER RABOVICH, ALEJANDRO MICHEL , Bin Peng , Liying Cui , Lily Song , Kris Rogers , Sandy Middleton , Joyce Y. Lim , Denise Forshaw , C. Elizabeth Lightbody , Mark Woodward , Octavio Pontes-Neto , H. Asita De Silva , Ruey-Tay Lin , Tsong-Hai Lee , Jeyaraj D. Pandian , Gillian E. Mead , Thompson Robinson , Caroline Watkins

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