BILLEKE BOBADILLA, PABLO ERNESTO
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BILLEKE BOBADILLA, PABLO ERNESTO
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pbilleke@udd.cl
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8229414600

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Publication

Theta and Alpha Oscillation Impairments in Autistic Spectrum Disorder Reflect Working Memory Deficit

2017 , Josefina Larrain-Valenzuela , ZAMORANO M, FRANCISCO JAVIER , SOTO ICAZA, PATRICIA , Ximena Carrasco , Claudia Herrera , Francisca Daiber , Francisco Aboitiz , BILLEKE BOBADILLA, PABLO ERNESTO

A dysfunction in the excitatory–inhibitory (E/I) coordination in neuronal assembly has been proposed as a possible neurobiological mechanism of Autistic Spectrum Disorder (ASD). However, the potential impact of this mechanism in cognitive performance is not fully explored. Since the main consequence of E/I dysfunction is an impairment in oscillatory activity and its underlying cognitive computations, we assessed the electroencephalographic activity of ASD and typically developing (TD) subjects during a working-memory task. We found that ASD subjects committed more errors than TD subjects. Moreover, TD subjects demonstrated a parametric modulation in the power of alpha and theta band while ASD subjects did not demonstrate significant modulations. The preceding leads to significant differences between the groups in both the alpha power placed on the occipital cortex and the theta power placed on the left premotor and the right prefrontal cortex. The impaired theta modulation correlated with autistic symptoms. The results indicated that ASD may present an alteration in the recruitment of the oscillatory activity during working-memory, and this alteration could be related to the physiopathology of the disorder.

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Impact of anthropometric nutritional parameters on the university selection test in Chile: A multifactorial approach

2019 , Daniza M. Ivanovic , Rodrigo B. Valenzuela , Atilio F. Almagià , Cynthia R. Barrera , Violeta C. Arancibia , Cristián G. Larraín , SILVA FUENTE ALBA, CLAUDIO SERGIO , BILLEKE BOBADILLA, PABLO ERNESTO , ZAMORANO M, FRANCISCO JAVIER , Francisca S. Villagrán , Yasna Z. Orellana , Víctor C. Martínez

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Functional Cortical Network in Alpha Band Correlates with Social Bargaining

2014 , BILLEKE BOBADILLA, PABLO ERNESTO , ZAMORANO M, FRANCISCO JAVIER , Mario Chavez , Diego Cosmelli , Francisco Aboitiz , Sam Doesburg

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Intra-Individual Response Variability Assessed by Ex-Gaussian Analysis may be a New Endophenotype for Attention-Deficit/Hyperactivity Disorder

2015 , Marcela Patricia Henríquez-Henríquez , BILLEKE BOBADILLA, PABLO ERNESTO , Hugo Henríquez , ZAMORANO M, FRANCISCO JAVIER , Francisco Rothhammer , Francisco Aboitiz

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Brain structural parameters correlate with University Selection Test outcomes in Chilean high school graduates

2022 , Daniza Ivanovic , ZAMORANO M, FRANCISCO JAVIER , SOTO ICAZA, PATRICIA , Tatiana Rojas , Atilio Almagià , SILVA FUENTE ALBA, CLAUDIO SERGIO , Claudia Bustamante , Violeta Arancibia , Francisca Villagrán , Rodrigo Valenzuela , Cynthia Barrera , Cristián Larraín , BILLEKE BOBADILLA, PABLO ERNESTO

AbstractHow well students learn and perform in academic contexts is a focus of interest for the students, their families, and the entire educational system. Although evidence has shown that several neurobiological factors are involved in scholastic achievement (SA), specific brain measures associated with academic outcomes and whether such associations are independent of other factors remain unclear. This study attempts to identify the relationship between brain structural parameters, and the Chilean national University Selection Test (PSU) results in high school graduates within a multidimensional approach that considers socio-economic, intellectual, nutritional, and demographic variables. To this end, the brain morphology of a sample of 102 students who took the PSU test was estimated using Magnetic Resonance Imaging. Anthropometric parameters, intellectual ability (IA), and socioeconomic status (SES) were also measured. The results revealed that, independently of sex, IA, gray matter volume, right inferior frontal gyrus thickness, and SES were significantly associated with SA. These findings highlight the role of nutrition, health, and socioeconomic variables in academic success.

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Docosahexaenoic acid levels in erythrocytes and their association with the University Selection Test Outcomes in Chile

2018 , Rodrigo Valenzuela , Cynthia Barrera , Yasna Orellana , Atilio Almagià , Violeta Arancibia , Cristián Larraín , SILVA FUENTE ALBA, CLAUDIO SERGIO , BILLEKE BOBADILLA, PABLO ERNESTO , ZAMORANO M, FRANCISCO JAVIER , Víctor Martínez , Alfonso Valenzuela , Daniza Ivanovic

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