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Now showing 1 - 10 of 34
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Topical Chemotherapy in Human Urothelial Carcinoma Explants: A Novel Translational Tool for Preclinical Evaluation of Experimental Intravesical Therapies

2009 , Christian Bolenz , Eva-Maria Ikinger , Philipp Ströbel , Lutz Trojan , Annette Steidler , FERNANDEZ ARANCIBIA, MARIO , Patrick Honeck , Ute Gabriel , Christel Weiss , Rainer Grobholz , Peter Alken , Maurice Stephan Michel

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Comparison of Oncologic Outcomes for Open and Laparoscopic Nephroureterectomy: A Multi-Institutional Analysis of 1249 Cases

2009 , Umberto Capitanio , Shahrokh F. Shariat , Hendrik Isbarn , Alon Weizer , Mesut Remzi , Marco Roscigno , Eiji Kikuchi , Jay D. Raman , Christian Bolenz , Karim Bensalah , Theresa M. Koppie , Wassim Kassouf , FERNANDEZ ARANCIBIA, MARIO , Philipp Ströbel , Jeffrey Wheat , Richard Zigeuner , Cord Langner , Matthias Waldert , Mototsugu Oya , Charles C. Guo , Casey Ng , Francesco Montorsi , Christopher G. Wood , Vitaly Margulis , Pierre I. Karakiewicz

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Postoperative morbidity of tubeless versus conventional percutaneous nephrolithotomy: a prospective comparative study

2011 , Fernando Marchant , Pedro Recabal , FERNANDEZ ARANCIBIA, MARIO , Francisco Osorio , Javiera Benavides

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Lymphovascular Invasion and Pathologic Tumor Stage Are Significant Outcome Predictors for Patients With Upper Tract Urothelial Carcinoma

2008 , Christian Bolenz , FERNANDEZ ARANCIBIA, MARIO , Lutz Trojan , Edwin Herrmann , Andreas Becker , Christel Weiss , Peter Alken , Philipp Ströbel , Maurice Stephan Michel

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Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ confined urothelial carcinoma following radical nephroureterectomy

2012 , Jeffery C. Wheat , Alon Z. Weizer , J. Stuart Wolf , Yair Lotan , Mesut Remzi , Vitaly Margulis , Christopher G. Wood , Francesco Montorsi , Marco Roscigno , Eiji Kikuchi , Richard Zigeuner , Cord Langner , Christian Bolenz , Theresa M. Koppie , Jay D. Raman , FERNANDEZ ARANCIBIA, MARIO , Pierre Karakiewizc , Umberto Capitanio , Karim Bensalah , Jean-Jacques Patard , Shahrokh F. Shariat

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Immediate postoperative morbidity in patients with indwelling double-J stent versus overnight-externalized ureteral catheter after tubeless percutaneous nephrolithotomy: a prospective, randomized study

2013 , Alejandro Mercado , FERNANDEZ ARANCIBIA, MARIO , Pedro Recabal , Daniela Fleck , Rodrigo Ledezma , Francisco Moya , Francisco Sepúlveda , Roberto Vilches , Diego Reyes , Fernando Marchant

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Tumour Necrosis Is an Indicator of Aggressive Biology in Patients with Urothelial Carcinoma of the Upper Urinary Tract

2010 , Richard Zigeuner , Shahrokh F. Shariat , Vitaly Margulis , Pierre I. Karakiewicz , Marco Roscigno , Alon Weizer , Eiji Kikuchi , Mesut Remzi , Jay D. Raman , Christian Bolenz , Karim Bensalah , Umberto Capitanio , Theresa M. Koppie , Wassim Kassouf , Kanishka Sircar , Jean-Jacques Patard , FERNANDEZ ARANCIBIA, MARIO , Christopher G. Wood , Francesco Montorsi , Philipp Ströbel , Jeffery C. Wheat , Andrea Haitel , Mototsugu Oya , Charles C. Guo , Casey Ng , Daher C. Chade , Arthur Sagalowsky , Cord Langner

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Long-Term Oncological and Functional Outcomes After Robot-Assisted Partial Nephrectomy for Clinically Localized Renal Cell Carcinoma

2022 , Hugo Otaola-Arca , Alfred Krebs , Hugo Bermúdez , Raúl Lyng , Marcelo Orvieto , Alberto Bustamante , Conrado Stein , LABRA WEITZLER, ANDRES ANTONIO , Marcela Schultz , FERNANDEZ ARANCIBIA, MARIO

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Postadmixture Selection on Chileans Targets Haplotype Involved in Pigmentation, Thermogenesis and Immune Defense against Pathogens

2020 , Lucas Vicuña , Olga Klimenkova , Tomás Norambuena , Felipe I Martinez , FERNANDEZ ARANCIBIA, MARIO , Vladimir Shchur , Susana Eyheramendy , Soojin Yi

Abstract Detection of positive selection signatures in populations around the world is helping to uncover recent human evolutionary history as well as the genetic basis of diseases. Most human evolutionary genomic studies have been performed in European, African, and Asian populations. However, populations with Native American ancestry have been largely underrepresented. Here, we used a genome-wide local ancestry enrichment approach complemented with neutral simulations to identify postadmixture adaptations underwent by admixed Chileans through gene flow from Europeans into local Native Americans. The top significant hits (P = 2.4×10−7) are variants in a region on chromosome 12 comprising multiple regulatory elements. This region includes rs12821256, which regulates the expression of KITLG, a well-known gene involved in lighter hair and skin pigmentation in Europeans as well as in thermogenesis. Another variant from that region is associated with the long noncoding RNA RP11-13A1.1, which has been specifically involved in the innate immune response against infectious pathogens. Our results suggest that these genes were relevant for adaptation in Chileans following the Columbian exchange.

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Impact of Lymph Node Dissection on Cancer Specific Survival in Patients With Upper Tract Urothelial Carcinoma Treated With Radical Nephroureterectomy

2009 , Marco Roscigno , Shahrokh F. Shariat , Vitaly Margulis , Pierre Karakiewicz , Mesut Remzi , Eiji Kikuchi , Cord Langner , Yair Lotan , Alon Weizer , Karim Bensalah , Jay D. Raman , Christian Bolenz , Charles C. Guo , Christopher G. Wood , Richard Zigeuner , Jeffrey Wheat , Wareef Kabbani , Theresa M. Koppie , Casey K. Ng , Nazareno Suardi , Roberto Bertini , FERNANDEZ ARANCIBIA, MARIO , Shuji Mikami , Masaru Isida , Maurice Stephan Michel , Francesco Montorsi