FERNANDEZ ARANCIBIA, MARIO
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FERNANDEZ ARANCIBIA, MARIO
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mariofernandez@udd.cl
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Scopus Author ID
7403378256

Research Output

2012 2012 2011 2011 2010 2010 2009 2009 2008 2008 0 0 2 2 4 4 6 6 8 8 10 10

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Topical Chemotherapy in Human Urothelial Carcinoma Explants: A Novel Translational Tool for Preclinical Evaluation of Experimental Intravesical Therapies

2009 , Christian Bolenz , Eva-Maria Ikinger , Philipp Ströbel , Lutz Trojan , Annette Steidler , FERNANDEZ ARANCIBIA, MARIO , Patrick Honeck , Ute Gabriel , Christel Weiss , Rainer Grobholz , Peter Alken , Maurice Stephan Michel

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Tumour Necrosis Is an Indicator of Aggressive Biology in Patients with Urothelial Carcinoma of the Upper Urinary Tract

2010 , Richard Zigeuner , Shahrokh F. Shariat , Vitaly Margulis , Pierre I. Karakiewicz , Marco Roscigno , Alon Weizer , Eiji Kikuchi , Mesut Remzi , Jay D. Raman , Christian Bolenz , Karim Bensalah , Umberto Capitanio , Theresa M. Koppie , Wassim Kassouf , Kanishka Sircar , Jean-Jacques Patard , FERNANDEZ ARANCIBIA, MARIO , Christopher G. Wood , Francesco Montorsi , Philipp Ströbel , Jeffery C. Wheat , Andrea Haitel , Mototsugu Oya , Charles C. Guo , Casey Ng , Daher C. Chade , Arthur Sagalowsky , Cord Langner

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Lymphangiogenesis occurs in upper tract urothelial carcinoma and correlates with lymphatic tumour dissemination and poor prognosis

2009 , Christian Bolenz , FERNANDEZ ARANCIBIA, MARIO , Lutz Trojan , Katja Hoffmann , Edwin Herrmann , Annette Steidler , Christel Weiss , Philipp Ströbel , Peter Alken , Maurice Stephan Michel

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Lymphovascular Invasion and Pathologic Tumor Stage Are Significant Outcome Predictors for Patients With Upper Tract Urothelial Carcinoma

2008 , Christian Bolenz , FERNANDEZ ARANCIBIA, MARIO , Lutz Trojan , Edwin Herrmann , Andreas Becker , Christel Weiss , Peter Alken , Philipp Ströbel , Maurice Stephan Michel

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Assessment of the Minimum Number of Lymph Nodes Needed to Detect Lymph Node Invasion at Radical Nephroureterectomy in Patients With Upper Tract Urothelial Cancer

2009 , Marco Roscigno , Shahrokh F. Shariat , Massimo Freschi , Vitaly Margulis , Pierre Karakiewizc , Nazareno Suardi , Mesut Remzi , Richard Zigeuner , Christian Bolenz , Eiji Kikuchi , Alon Weizer , Karim Bensalah , Arthur Sagalowsky , Theresa M. Koppie , Jay Raman , FERNANDEZ ARANCIBIA, MARIO , Philipp Ströbel , Wareef Kabbani , Cord Langner , Jeffery Wheat , Charles C. Guo , Wassim Kassouf , Andrea Haitel , Christopher G. Wood , Francesco Montorsi

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Lymphovascular Invasion Predicts Clinical Outcomes in Patients With Node-Negative Upper Tract Urothelial Carcinoma

2009 , Eiji Kikuchi , Vitaly Margulis , Pierre I. Karakiewicz , Marco Roscigno , Shuji Mikami , Yair Lotan , Mesut Remzi , Christian Bolenz , Cord Langner , Alon Weizer , Francesco Montorsi , Karim Bensalah , Theresa M. Koppie , FERNANDEZ ARANCIBIA, MARIO , Jay D. Raman , Wassim Kassouf , Christopher G. Wood , Nazareno Suardi , Mototsugu Oya , Shahrokh F. Shariat

To assess the association of lymphovascular invasion (LVI) with cancer recurrence and survival in a large international series of patients treated with radical nephroureterectomy (RNU) for upper urinary tract urothelial carcinoma (UTUC). Patients and Methods Data were collected on 1,453 patients treated with RNU at 13 academic centers and combined into a relational database. Pathologic slides were rereviewed by genitourinary pathologists according to strict criteria. LVI was defined as presence of tumor cells within an endothelium-lined space. Results LVI was observed in 349 patients (24%). Proportion of LVI increased with advancing tumor stage, high tumor grade, presence of tumor necrosis, sessile tumor architecture, and presence of lymph node metastasis (all P < .001). LVI was an independent predictor of disease recurrence and survival (P < .001 for both). Addition of LVI to the base model (comprising pathologic stage, grade, and lymph node status) marginally improved its predictive accuracy for both disease recurrence and survival (1.1%, P = .03; and 1.7%, P < .001, respectively). In patients with negative lymph nodes and those in whom a lymphadenectomy was not performed (n = 1,313), addition of LVI to the base model improved the predictive accuracy of the base model for both disease recurrence and survival by 3% (P < .001 for both). In contrast, LVI was not associated with disease recurrence or survival in node-positive patients (n = 140). Conclusion LVI was an independent predictor of clinical outcomes in nonmetastatic patients who underwent RNU for UTUC. Assessment of LVI may help identify patients who could benefit from multimodal therapy after RNU. After confirmation, LVI should be included in staging of UTUC.

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The Extent of Lymphadenectomy Seems to Be Associated with Better Survival in Patients with Nonmetastatic Upper-Tract Urothelial Carcinoma: How Many Lymph Nodes Should Be Removed?

2009 , Marco Roscigno , Shahrokh F. Shariat , Vitaly Margulis , Pierre Karakiewicz , Mesut Remzi , Eiji Kikuchi , Richard Zigeuner , Alon Weizer , Arthur Sagalowsky , Karim Bensalah , Jay D. Raman , Christian Bolenz , Wassim Kassou , Theresa M. Koppie , Christopher G. Wood , Jeffrey Wheat , Cord Langner , Casey K. Ng , Umberto Capitanio , Roberto Bertini , FERNANDEZ ARANCIBIA, MARIO , Shuji Mikami , Masaru Isida , Philipp Ströbel , Francesco Montorsi

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Adjuvant Chemotherapy for High Risk Upper Tract Urothelial Carcinoma: Results From the Upper Tract Urothelial Carcinoma Collaboration

2009 , Nicholas J. Hellenthal , Shahrokh F. Shariat , Vitaly Margulis , Pierre I. Karakiewicz , Marco Roscigno , Christian Bolenz , Mesut Remzi , Alon Weizer , Richard Zigeuner , Karim Bensalah , Casey K. Ng , Jay D. Raman , Eiji Kikuchi , Francesco Montorsi , Mototsugu Oya , Christopher G. Wood , FERNANDEZ ARANCIBIA, MARIO , Christopher P. Evans , Theresa M. Koppie

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The role of lymphangiogenesis in lymphatic tumour spread of urological cancers

2009 , Christian Bolenz , FERNANDEZ ARANCIBIA, MARIO , Derya Tilki , Edwin Herrmann , Julia Heinzelbecker , Süleyman Ergün , Philipp Ströbel , Oliver Reich , Maurice S. Michel , Lutz Trojan

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Concomitant carcinoma in situ is a feature of aggressive disease in patients with organ confined urothelial carcinoma following radical nephroureterectomy

2012 , Jeffery C. Wheat , Alon Z. Weizer , J. Stuart Wolf , Yair Lotan , Mesut Remzi , Vitaly Margulis , Christopher G. Wood , Francesco Montorsi , Marco Roscigno , Eiji Kikuchi , Richard Zigeuner , Cord Langner , Christian Bolenz , Theresa M. Koppie , Jay D. Raman , FERNANDEZ ARANCIBIA, MARIO , Pierre Karakiewizc , Umberto Capitanio , Karim Bensalah , Jean-Jacques Patard , Shahrokh F. Shariat

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