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Scrub typhus in Tierra del Fuego: a tropical rickettsiosis in a subantarctic region

2021 , WEITZEL, THOMAS , AYLWIN RAMIREZ, MABEL CRISTINA , Constanza Martínez-Valdebenito , Gerardo Acosta-Jamett , Katia Abarca

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Imported scrub typhus: first case in South America and review of the literature

2018 , WEITZEL, THOMAS , AYLWIN RAMIREZ, MABEL CRISTINA , Constanza Martínez-Valdebenito , Ju Jiang , THOMPSON MOYA, LUIS ADALBERTO , MUNITA SEPULVEDA, JOSE MANUEL , Katia Abarca , Allen L. Richards

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Covid-19 in South America: clinical and epidemiological characteristics among 381 patients during the early phase of the pandemic in Santiago, Chile

2020 , Macarena R. Vial , Anne Peters , Inia Pérez , María Spencer-Sandino , Mario Barbé , PORTE TORRE, LORENA ISABEL , WEITZEL, THOMAS , AYLWIN RAMIREZ, MABEL CRISTINA , VIAL CLARO, PABLO AGUSTIN , ARAOS BRALIC, RAFAEL IGNACIO , MUNITA SEPULVEDA, JOSE MANUEL

Abstract Background Understanding the characteristics of the Covid-19 pandemic in different geographical regions, ethnic and socioeconomic settings are of emerging importance. This study presents the demographic and clinical features of SARS-CoV-2 infected patients in a large private healthcare center in Santiago, Chile, during the first month of the pandemic. Methods We analyzed the demographics, laboratory and clinical characteristics including severity and outcome of all patients diagnosed with Covid-19 during the first month of the pandemic. SARS-2-CoV infection was confirmed by RT-PCR in nosopharyngeal samples. The primary outcome was a composite of ICU admission or all-cause, in-hospital mortality. Clinical and laboratory parameters of hospitalized patients were analyzed regarding their association with the primary outcome. Results From March 3 to April 4, 2020, 3679 individuals were tested for SARS-CoV-2 in our hospital. Of those, 381 had Covid-19 and were included into this analysis. Most patients (99.2%) were Chileans, 12% returning from recent travel. The median age was 39 years (IQR 31–49) and 52% were female. A total of 88 patients (23.1%) were hospitalized; 18 (3.7%) required ICU and/or died. The overall mortality was 0.7%. Increased body mass index (BMI) and elevated C-reactive protein (CRP) were independently associated with ICU care or death. Conclusion During the first weeks of the pandemic in Chile, most Covid-19 patients were young, with low rates of hospitalization, ICU requirement, and fatality. BMI and CRP on admission were predictors for severity. Our data provide important information on the clinical course and outcome of Covid-19 in a Latin American setting.

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Papular‐purpuric exanthem in a COVID‐19 patient: clinical and dermoscopic description

2020 , JORGE FELIPE LARRONDO GALVEZ , CABRERA MORAGA, RAUL ALEJANDRO , M. Gosch , F. Larrondo , AYLWIN RAMIREZ, MABEL CRISTINA , CASTRO MENDEZ, ALEX

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First Report of Tocilizumab Use in a Cohort of Latin American Patients Hospitalized for Severe COVID-19 Pneumonia

2020 , VALENZUELA LETELIER, OMAR ANTONIO , IBAÑEZ, SEBASTIAN , M. Cecilia Poli , ROESSLER VERGARA, PATRICIA ANDREA , AYLWIN RAMIREZ, MABEL CRISTINA , Gigia Roizen , IRURETAGOYENA BRUCE, MIRENTXU INES , Vivianne Agar , Javiera Donoso , Margarita Fierro , José Montes