UNDURRAGA FOURCADE, JUAN PABLO
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UNDURRAGA FOURCADE, JUAN PABLO
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jundurraga@udd.cl
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33568392600

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Emotional intelligence: a comparison between patients after first episode mania and those suffering from chronic bipolar disorder type I

2022 , Cristina Varo , Silvia Amoretti , Giulio Sparacino , Esther Jiménez , Brisa Solé , Caterina del Mar Bonnin , Laura Montejo , Maria Serra , Carla Torrent , Estela Salagre , Antoni Benabarre , Pilar Salgado-Pineda , Irene Montoro Salvatierra , Pilar A. Sáiz , María Paz García-Portilla , Vanessa Sánchez-Gistau , Edith Pomarol-Clotet , Josep Antoni Ramos-Quiroga , Isabella Pacchiarotti , Clemente Garcia-Rizo , UNDURRAGA FOURCADE, JUAN PABLO , María Reinares , Anabel Martinez-Aran , Eduard Vieta , Norma Verdolini

Abstract Background Deficits in emotional intelligence (EI) were detected in patients with bipolar disorder (BD), but little is known about whether these deficits are already present in patients after presenting a first episode mania (FEM). We sought (i) to compare EI in patients after a FEM, chronic BD and healthy controls (HC); (ii) to examine the effect exerted on EI by socio-demographic, clinical and neurocognitive variables in FEM patients. Methods The Emotional Intelligence Quotient (EIQ) was calculated with the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT). Performance on MSCEIT was compared among the three groups using generalized linear models. In patients after a FEM, the influence of socio-demographic, clinical and neurocognitive variables on the EIQ was examined using a linear regression model. Results In total, 184 subjects were included (FEM n = 48, euthymic chronic BD type I n = 75, HC n = 61). BD patients performed significantly worse than HC on the EIQ [mean difference (MD) = 10.09, standard error (s.e.) = 3.14, p = 0.004] and on the understanding emotions branch (MD = 7.46, s.e. = 2.53, p = 0.010). FEM patients did not differ from HC and BD on other measures of MSCEIT. In patients after a FEM, EIQ was positively associated with female sex (β = −0.293, p = 0.034) and verbal memory performance (β = 0.374, p = 0.008). FEM patients performed worse than HC but better than BD on few neurocognitive domains. Conclusions Patients after a FEM showed preserved EI, while patients in later stages of BD presented lower EIQ, suggesting that impairments in EI might result from the burden of disease and neurocognitive decline, associated with the chronicity of the illness.

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Self-monitoring and psychoeducation in bipolar patients with a smart-phone application (SIMPLe) project: design, development and studies protocols

2015 , Diego Hidalgo-Mazzei , Ainoa Mateu , María Reinares , Juan Undurraga , Caterina del Mar Bonnín , José Sánchez-Moreno , Eduard Vieta , Francesc Colom

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Predictors of functional outcome after a manic episode

2015 , C. Mar Bonnín , María Reinares , Diego Hidalgo-Mazzei , Juan Undurraga , Maria Mur , Cristina Sáez , Evaristo Nieto , Gustavo H. Vázquez , Vicent Balanzá-Martínez , Rafael Tabarés-Seisdedos , Eduard Vieta

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A 12-month prospective study on the time to hospitalization and clinical management of a cohort of bipolar type I and schizoaffective bipolar patients

2019 , Andrea Murru , Norma Verdolini , Gerard Anmella , Isabella Pacchiarotti , Ludovic Samalin , Alberto Aedo , UNDURRAGA FOURCADE, JUAN PABLO , José M. Goikolea , Benedikt L Amann , Andre F. Carvalho , Eduard Vieta

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Clinical characterization of rapid cycling bipolar disorder: Association with attention deficit hyperactivity disorder

2018 , Alberto Aedo , Andrea Murru , Raúl Sanchez , Iria Grande , Eduard Vieta , Juan Undurraga

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Prodromal phase: Differences in prodromal symptoms, risk factors and markers of vulnerability in first episode mania versus first episode psychosis with onset in late adolescence or adulthood

2022 , Norma Verdolini , Roger Borràs , Giulio Sparacino , Marina Garriga , Maria Sagué‐Vilavella , Santiago Madero , Roberto Palacios‐Garrán , Maria Serra , Maria Florencia Forte , Estela Salagre , Alberto Aedo , Pilar Salgado‐Pineda , Irene Montoro Salvatierra , Vanessa Sánchez Gistau , Edith Pomarol‐Clotet , Josep Antoni Ramos‐Quiroga , Andre F. Carvalho , Clemente Garcia‐Rizo , UNDURRAGA FOURCADE, JUAN PABLO , María Reinares , Anabel Martinez Aran , Miguel Bernardo , Eduard Vieta , Isabella Pacchiarotti , Silvia Amoretti

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Shaped before birth: Obstetric complications identify a more severe clinical phenotype among patients presenting a first affective or non-affective episode of psychosis

2022 , Maria Sagué-Vilavella , Silvia Amoretti , Marina Garriga , Gisela Mezquida , Evelyn Williams , Maria Serra-Navarro , Maria Florencia Forte , Cristina Varo , Laura Montejo , Roberto Palacios-Garran , Santiago Madero , Giulio Sparacino , Gerard Anmella , Giovanna Fico , Anna Giménez-Palomo , Maria Teresa Pons-Cabrera , Pilar Salgado-Pineda , Irene Montoro Salvatierra , Vanessa Sánchez Gistau , Edith Pomarol-Clotet , Josep Antoni Ramos-Quiroga , UNDURRAGA FOURCADE, JUAN PABLO , María Reinares , Anabel Martínez-Arán , Isabella Pacchiarotti , Isabel Valli , Miguel Bernardo , Clemente Garcia-Rizo , Eduard Vieta , Norma Verdolini

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Making sense of DSM-5 mania with depressive features

2015 , María Reinares , Caterina del Mar Bonnín , Diego Hidalgo-Mazzei , Juan Undurraga , Maria Mur , Evaristo Nieto , Cristina Sáez , Eduard Vieta

Objective: The assessment of the depressive component during mania has become critical for the accurate diagnosis of mixed states, which were defined very narrowly in the past classification systems before Diagnostic and Statistical Manual of Mental Disorders (5th ed.). The aim of this study was to compare socio-demographic, clinical and therapeutic characteristics, as well as clinical and functional outcomes, between manic patients with and without mixed features to validate the relevance of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.) mixed specifier. Methods: This is a subanalysis of a multicentre naturalistic study MANía Aguda y COnsumo de Recursos (acute mania and health resource consumption [MANACOR]) on the burden of mania in bipolar patients from four hospitals in Catalonia (Spain). The sample consisted of 169 adult patients presenting a manic episode and systematically assessed during a 6-month period. Results: A total of 27% ( n = 46/169) of manic patients showed mixed features. Total number of episodes ( p = 0.027), particularly depressive and mixed, was greater in manic patients with mixed features, as well as depressive onset ( p = 0.018), suicide ideation ( p = 0.036), rapid cycling ( p = 0.035) and personality disorders ( p = 0.071). In contrast, a higher percentage of pure manic subjects were inpatients ( p = 0.035), started the illness with mania ( p = 0.018) and showed family history of bipolar disorder ( p = 0.037), congruent psychotic symptoms ( p = 0.001) and cannabis use ( p = 0.006). At baseline, pure manic patients received more risperidone ( p = 0.028), while mixed patients received more valproate ( p = 0.049) and antidepressants ( p = 0.005). No differences were found in syndromic recovery at the end of the study. However, depressive change was higher in the mixed group ( p = 0.010), while manic change was higher in the pure manic group ( p = 0.029). At the end of follow-up, the group with mixed features showed a significant trend towards higher psychosocial dysfunction. Conclusion: A total of 27% of manic patients showed mixed features. Groups differed regarding clinical characteristics, course of illness, psychosocial functioning, prescribed treatment and symptom progress. Depressive symptoms in mania should be routinely assessed and considered to guide treatment.

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Risk factors for rapid cycling in bipolar disorder

2015 , Marc Valentí , Isabella Pacchiarotti , Juan Undurraga , C Mar Bonnín , Dina Popovic , José M Goikolea , Carla Torrent , Diego Hidalgo-Mazzei , Francesc Colom , Eduard Vieta

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e-HCL-32: a useful, valid and user friendly tool in the screening of bipolar II disorder

2015 , Diego Hidalgo-Mazzei , Ainoa Mateu , UNDURRAGA FOURCADE, JUAN PABLO , Adriane R. Rosa , Isabella Pacchiarotti , Caterina del Mar Bonnin , José Sánchez-Moreno , Francesc Colom , Eduard Vieta

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