GONZALEZ COFRE, FERNANDO OMAR
Thumbnail Image
Preferred name
GONZALEZ COFRE, FERNANDO OMAR
Main Affiliation
Email
fgonzalezcofre@udd.cl

Research Output

2024 2024 2023 2023 2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 0.0 0.0 0.5 0.5 1.0 1.0 1.5 1.5 2.0 2.0 2.5 2.5 3.0 3.0

Filters

8
Reset filters

Settings
Now showing 1 - 8 of 8
No Thumbnail Available
Publication

MRI/TRUS fusion vs. systematic biopsy: intra-patient comparison of diagnostic accuracy for prostate cancer using PI-RADS v2

2020 , Andrés Labra , Claudio Silva , Fernando González , Gerhard Franz , Rodrigo Pinochet , Rajan T. Gupta

View
No Thumbnail Available
Publication

Switching Stable Kidney Transplant Recipients to a Generic Tacrolimus Is Feasible and Safe, but It Must Be Monitored

2017 , Fernando González , Elizabeth Arriagada , René López , René Carrasco , NATALIA BERNARDITA GALLARDO CHAPARRO , Eduardo Lorca

Background. Tacrolimus is the primary immunosuppressive drug used in kidney transplant patients. Replacing brand name products with generics is a controversial issue that we studied after a Chilean Ministry of Health mandate to implement such a switch.Methods. Forty-one stable Prograf (Astellas) receiving kidney transplant patients were switched to a generic tacrolimus (Sandoz) in a 1 : 1 dose ratio and were followed up for up to 8 months. All other drugs were maintained as per normal practice.Results. Neither tacrolimus doses nor their trough blood levels changed significantly after the switch, but serum creatinine did:1.62±0.90versus1.75±0.92 mg/dL (p<0.001). At the same time, five graft biopsies were performed, and two of them showed cellular acute rejection. There were nine infectious episodes treated satisfactorily with proper therapies. No patient or graft was lost during the follow-up time period.Conclusion. Switching from brand name tacrolimus to a generic tacrolimus (Sandoz) is feasible and appears to be safe, but it must be monitored carefully by treating physicians.

View
No Thumbnail Available
Publication

Correlation of preoperative imaging characteristics with donor outcomes and operative difficulty in laparoscopic donor nephrectomy

2020 , Fides R. Schwartz , Brian I. Shaw , Reginald Lerebours , Federica Vernuccio , Francesca Rigiroli , GONZALEZ COFRE, FERNANDO OMAR , Sheng Luo , Aparna S. Rege , Deepak Vikraman , Lynne Hurwitz‐Koweek , Daniele Marin , Kadiyala Ravindra

View
No Thumbnail Available
Publication

Secondary rectal linitis plastica caused by prostatic adenocarcinoma - magnetic resonance imaging findings and dissemination pathways: A case report

2024 , LABRA WEITZLER, ANDRES ANTONIO , SCHIAPPACASSE FAUNDES, GIANCARLO , Rolando Alfonso Cocio , Jorge Tomás Torres , GONZALEZ COFRE, FERNANDO OMAR , Alberto Cristi , Marcela Schultz

BACKGROUND Secondary rectal linitis plastica (RLP) from prostatic adenocarcinoma is a rare and poorly understood form of metastatic spread, characterized by a desmoplastic response and concentric rectal wall infiltration with mucosal preservation. This complicates endoscopic diagnosis and can mimic gastrointestinal malignancies. This case series underscores the critical role of magnetic resonance imaging (MRI) in identifying the distinct imaging features of RLP and highlights the importance of considering this condition in the differential diagnosis of patients with a history of prostate cancer. CASE SUMMARY Three patients with secondary RLP due to prostatic adenocarcinoma presented with varied clinical features. The first patient, a 76-year-old man with advanced prostate cancer, had rectal pain and incontinence. MRI showed diffuse prostatic invasion and significant rectal wall thickening with a characteristic "target sign" pattern. The second, a 57-year-old asymptomatic man with elevated prostate-specific antigen levels and a history of prostate cancer exhibited rectoprostatic angle involvement and rectal wall thickening on MRI, with positron emission tomography/computed tomography PSMA confirming the prostatic origin of the metastatic spread. The third patient, an 80-year-old post-radical prostatectomy, presented with refractory constipation. MRI revealed a neoplastic mass infiltrating the rectal wall. In all cases, MRI consistently showed stratified thickening, concentric signal changes, restricted diffusion, and contrast enhancement, which were essential for diagnosing secondary RLP. Biopsies confirmed the prostatic origin of the neoplastic involvement in the rectum. CONCLUSION Recognizing MRI findings of secondary RLP is essential for accurate diagnosis and management in prostate cancer patients.

View
No Thumbnail Available
Publication

Virtual Unenhanced Images at Dual-Energy CT: Influence on Renal Lesion Characterization

2019 , Mathias Meyer , Rendon C. Nelson , Federica Vernuccio , GONZALEZ COFRE, FERNANDO OMAR , Alfredo E. Farjat , Bhavik N. Patel , Ehsan Samei , Thomas Henzler , Stefan O. Schoenberg , Daniele Marin

View
No Thumbnail Available
Publication

Variability of quantitative measurements of metastatic liver lesions: a multi-radiation-dose-level and multi-reader comparison

2020 , Yuqin Ding , Daniele Marin , Federica Vernuccio , GONZALEZ COFRE, FERNANDO OMAR , Hannah V. Williamson , Hans-Christoph Becker , Bhavik N. Patel , Justin Solomon , Juan Carlos Ramirez-Giraldo , Ehsan Samei , Rendon C. Nelson , Mathias Meyer

View
No Thumbnail Available
Publication

LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arterial Phase Hyperenhancement

2019 , Federica Vernuccio , Roberto Cannella , Mathias Meyer , Kingshuk Roy Choudhoury , Fernando Gonzáles , Fides R. Schwartz , Rajan T. Gupta , Mustafa R. Bashir , Alessandro Furlan , Daniele Marin , GONZALEZ COFRE, FERNANDO OMAR

View
No Thumbnail Available
Publication

Comparison of Iodine Quantification and Conventional Attenuation Measurements for Differentiating Small, Truly Enhancing Renal Masses From High-Attenuation Nonenhancing Renal Lesions With Dual-Energy CT

2019 , Mathias Meyer , Rendon C. Nelson , Federica Vernuccio , GONZALEZ COFRE, FERNANDO OMAR , Christoph Schabel , Achille Mileto , Bhavik N. Patel , Stefan O. Schoenberg , Daniele Marin

View