Research Output

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Over 50% of self-reported burnout among Latin American orthopaedic surgeons: A cross-sectional survey on prevalence and risk factors

2024 , VAISMAN BURUCKER, ALEJANDRO ESTEBAN , Rodrigo Guiloff , Martín Contreras , Juan Pablo Casas-cordero , CALVO RODRIGUEZ, RAFAEL , FIGUEROA POBLETE, DAVID HUMBERTO

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Intraarticular Administration of Dexamethasone after Mesenchymal Stem Cells Implantation Does Not Improve Significantly the Treatment of Preestablished Full-Thickness Chondral Defect in a Rabbit Model

2013 , Maximiliano Espinosa , Alex Vaisman , Nicolas Nazal , FIGUEROA POBLETE, DAVID HUMBERTO , Marcela Gallegos , CONGET MOLINA, PAULETTE ANDREA

Objective: The aim of this study was to evaluate the contribution to hyaline cartilage regeneration of dexamethasone intraarticular administration after autologous mesenchymal stem cells (MSCs) implantation into a preestablished knee full-thickness chondral defect. Design: Full-thickness chondral defects of 4.5 × 4.5 mm2 were surgically made in both medial femoral condyles of adult male New Zealand rabbits. Two weeks later, autologous ex vivo expanded bone marrow–derived MSCs were embedded in hyaluronic acid and implanted into the chondral defects. Immediately and every week after the intervention, dexamethasone 0.25 mg/kg was intraarticularly administered (MSC/dexa-treated group). Six weeks after MSC transplantation, the animals were euthanized and condyles were characterized molecularly according to aggrecan, collagen type II, and collagen type I gene expression (quantitative reverse transcriptase-polymerase chain reaction) and histologically (hematoxylin–eosin staining). Data of MSC/dexa-treated condyles were compared with untreated, dexa-treated, MSC-treated, or normal unlesioned condyles. Results: The ratio between collagen type II expression versus collagen type I expression in MSC/dexa-treated condyles was higher than one, even though the group mean value was not statistically different from that of untreated defects. Histological changes were observed between MSC/dexa-treated and untreated defects mainly in surface regularity and in hyaline matrix abundance. However, International Cartilage Repair Society score analysis did not support robust differences between those groups. Conclusion: Intraarticular administration of dexamethasone after autologous MSC implantation into a preestablished full-thickness chondral defect does not contribute significantly to the regeneration of a tissue with molecular and histological characteristics identical to hyaline cartilage.

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Uso del plasma rico en plaquetas en cirugía ligamentosa de rodilla

2013 , FIGUEROA POBLETE, DAVID HUMBERTO , FIGUEROA BERRIOS, FRANCISCO JAVIER , Ahumada P Ximena , CALVO RODRIGUEZ, RAFAEL , Alex Vaisman B

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Cerebral and pulmonary fat embolism after unilateral total knee arthroplasty

2019 , FIGUEROA POBLETE, DAVID HUMBERTO , FIGUEROA BERRIOS, FRANCISCO JAVIER , Rafael Calvo Mena , Figueroa, María

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In TKA, Lower Versus Higher Tourniquet Inflation Pressures Reduced Postoperative Pain at the Tourniquet Inflation Site and Surgical Site at 24 and 48 Hours and 2 Weeks

2021 , FIGUEROA POBLETE, DAVID HUMBERTO

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Aloinjertos óseos y la función del banco de huesos

2011 , CALVO RODRIGUEZ, RAFAEL , FIGUEROA POBLETE, DAVID HUMBERTO , Claudio Díaz-Ledezma , Alex Vaisman , FIGUEROA BERRIOS, FRANCISCO JAVIER

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Single time angular deformity correction and treatment of knee instability in congenital fibular hemimelia. A case report

2012 , FIGUEROA POBLETE, DAVID HUMBERTO , Villalón, Ignacio E. , CALVO RODRIGUEZ, RAFAEL , Schmidt-Hebbel, Andrés , Baar, Alejandro , FIGUEROA BERRIOS, FRANCISCO JAVIER

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Posterolateral corner knee injuries: a narrative review

2021 , FIGUEROA BERRIOS, FRANCISCO JAVIER , FIGUEROA POBLETE, DAVID HUMBERTO , Sven Putnis , Rodrigo Guiloff , Patricio Caro , João Espregueira-Mendes

Limited knowledge of the anatomy and biomechanics of the posterolateral corner (PLC) of the knee, coupled with poor patient outcomes with non-operative management, resulted in the PLC often being labelled as the ‘dark side’ of the knee. In the last two decades, extensive research has resulted in a better understanding of the anatomy and function of the PLC, and has led to the development of anatomic reconstructions that have resulted in improved patient outcomes. Despite considerable attention in the clinical orthopaedic literature (nearly 400 articles published in the last decade), a standardized algorithm for the diagnosis and treatment of the PLC is still lacking, and much controversy remains. Considering the literature review, there is not a reconstruction technique that clearly prevails over the others. As anatomic, biomechanical, and clinical knowledge of PLC injuries continues to progress, finding the balance between re-creating native anatomy and safely performing PLC reconstruction provides a big challenge. Treatment decisions should be made on a case-by-case basis.Cite this article: EFORT Open Rev 2021;6:676-685. DOI: 10.1302/2058-5241.6.200096

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Patrón de revascularización de injertos de tendones flexores rotos en reconstrucción de ligamento cruzado anterior: un estudio histológico

2016 , FIGUEROA POBLETE, DAVID HUMBERTO , R. Martínez , CALVO RODRIGUEZ, RAFAEL , M. Scheu , M. Gallegos , VAISMAN BURUCKER, ALEJANDRO ESTEBAN , C. Martínez , A. González

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Isokinetic assessment post-ACL reconstruction: comparison of the semitendinous/gracilis and bone-tendon-bone techniques

2009 , FIGUEROA POBLETE, DAVID HUMBERTO , Meleán Quiroga, Patricio , CALVO RODRIGUEZ, RAFAEL , Vaisman Burucker, Alex , FIGUEROA BERRIOS, FRANCISCO JAVIER , Calvo Cabiati, Claudia

The purpose of this study is to detect the differences in the isokinetic assessment after anterior cruciate ligament (ACL) reconstruction with the bone-patellar tendon-bone (BTB) and semitendinous/gracilis (STG) techniques.