Research Output

2023 2023 2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 2016 2016 2015 2015 2014 2014 0.0 0.0 1.0 1.0 2.0 2.0 3.0 3.0 4.0 4.0 5.0 5.0 6.0 6.0
Now showing 1 - 10 of 16
No Thumbnail Available
Product

Dataset - Immunization and SARS-CoV-2 Antibody Seroprevalence in a Country with High Vaccination Coverage: Lessons from Chile

2022 , AGUILERA SANHUEZA, XIMENA PAZ , GONZALEZ WIEDMAIER, CLAUDIA MARTA , APABLAZA SALINAS, MAURICIO IVÁN , RUBILAR RAMIREZ, PAOLA ANDREA , CORTES SALINAS, LINA JIMENA

No Thumbnail Available
Publication

Clinical features and prognostic factors of meningococcal disease: a case series study in Chile during the 2012-2013 outbreak

2015 , MATUTE WILLEMSEM, MARIA ISABEL , OLEA NORMANDIN, ANDREA MARIA , Darío López , Sergio Loayza , Manuel Nájera , GONZALEZ WIEDMAIER, CLAUDIA MARTA , Lucy Poffald , DELGADO BECERRA, OROZIMBA IRIS , HIRMAS ADAUY, MACARENA SOLEDAD , Elena Pedroni , Tania Alfaro , Ana María Gormaz , Gabriel Sanhueza , Jeannette Dabanch , Doris Gallegos , VIAL CLARO, PABLO AGUSTIN , AGUILERA SANHUEZA, XIMENA PAZ

No Thumbnail Available
Publication

Compliance with the smoking ban in urban public transportation in Chile

2020 , PERUGA URREA, ARMANDO , Xaviera Molina , DELGADO BECERRA, OROZIMBA IRIS , Oscar Urrejola , MATUTE WILLEMSEM, MARIA ISABEL , OLEA NORMANDIN, ANDREA MARIA , HIRMAS ADAUY, MACARENA SOLEDAD , GONZALEZ WIEDMAIER, CLAUDIA MARTA , AGUILERA SANHUEZA, XIMENA PAZ

No Thumbnail Available
Publication

Factors influencing neutralizing antibody response to the original SARS-CoV-2 virus and the Omicron variant in a high vaccination coverage country, a population-based study

2023 , HORMAZABAL CASTILLO, JUAN PATRICIO , Loreto Nuñez-Franz , RUBILAR RAMIREZ, PAOLA ANDREA , APABLAZA SALINAS, MAURICIO IVÁN , VIAL COX, MARIA CECILIA , CORTES SALINAS, LINA JIMENA , Macarena Said , Kathya Olivares , VIAL CLARO, PABLO AGUSTIN , Muriel Ramírez-Santana , GONZALEZ WIEDMAIER, CLAUDIA MARTA , Natalia González , AGUILERA SANHUEZA, XIMENA PAZ

No Thumbnail Available
Publication

Compliance with the smoking ban in enclosed, semiopen and open areas of workplaces and public places in Chile

2020 , PERUGA URREA, ARMANDO , Xaviera Molina , DELGADO BECERRA, OROZIMBA IRIS , MATUTE WILLEMSEM, MARIA ISABEL , OLEA NORMANDIN, ANDREA MARIA , HIRMAS ADAUY, MACARENA SOLEDAD , GONZALEZ WIEDMAIER, CLAUDIA MARTA , AGUILERA SANHUEZA, XIMENA PAZ

ObjectiveTo assess the national level of compliance with the Chilean comprehensive smoke-free legislation by observing healthcare facilities, education centres, government offices, hospitality venues and private workplaces, by type of area within workplaces and public places: enclosed, semiopen and open.MethodologyIn this cross-sectional observational study, we studied a national representative sample of 3253 venues obtained through a two-stage cluster sampling design. First, 57 municipalities were randomly selected, proportionally to the total number of venues of interest. Second, within each selected municipality, a maximum of 12 venues of each sector was selected systematically from a list of existing sites. We determined the non-compliance level by estimating the percentage of the visited venues where smoking was observed or suspected in banned areas of the premises.ResultsSmoking or suspicion thereof was not observed in any enclosed area of any establishment. However, smoking violations were observed in semiopen areas ranging from less than 0.5% of schools and healthcare centres to around 10% of hospitality venues or 23.0% of higher education centres. Smoking violations were also observed in outdoor areas of 6.7% and 1.6% of the health centres and schools, respectively.DiscussionThe stark contrast in compliance with the smoking ban between the enclosed areas and the semiopen areas may be a consequence of the complex definition of semiopen areas in the regulations. The study also reflects the need to improve the overall enforcement of the smoke-free law, particularly in universities and hospitality venues.

No Thumbnail Available
Publication

Actualización en el diagnóstico y manejo de la Infección Urinaria en pediatría

2012 , Paulina Salas del C , Patricia Barrera B , Claudia González C , Pedro Zambrano O , Ignacio Salgado D , Lily Quiroz , Ana María Lillo D , Pilar Hevia J , CARLOS FELIPE GONZALO CAVAGNARO SANTA MARIA

No Thumbnail Available
Publication

Seroprevalence, spatial distribution, and social determinants of SARS-CoV-2 in three urban centers of Chile

2022 , VIAL CLARO, PABLO AGUSTIN , GONZALEZ WIEDMAIER, CLAUDIA MARTA , Gloria Icaza , Muriel Ramirez-Santana , Rubén Quezada-Gaete , Loreto Núñez-Franz , VIAL COX, MARIA CECILIA , APABLAZA SALINAS, MAURICIO IVÁN , RUBILAR RAMIREZ, PAOLA , Juan Correa , PEREZ ACUÑA, CLAUDIA VERONICA , Andrei Florea , Eugenio Guzmán , María-Estela Lavín , Paula Concha , Manuel Nájera , AGUILERA SANHUEZA, XIMENA PAZ

Abstract Background Seroprevalence studies provide an accurate measure of SARS-CoV-2 spread and the presence of asymptomatic cases. They also provide information on the uneven impact of the pandemic, pointing out vulnerable groups to prioritize which is particularly relevant in unequal societies. However, due to their high cost, they provide limited evidence of spatial spread of the pandemic specially in unequal societies. Our objective was to estimate the prevalence of SARS-CoV-2 antibodies in Chile and model its spatial risk distribution. Methods During Oct–Nov 2020, we conducted a population-based serosurvey in Santiago, Talca, and Coquimbo–La Serena (2493 individuals). We explored the individual association between positive results and socio-economic and health-related variables by logistic regression for complex surveys. Then, using an Empirical Bayesian Kriging model, we estimated the infection risk spatial distribution using individual and census information, and compared these results with official records. Results Seroprevalence was 10.4% (95% CI 7.8–13.7%), ranging from 2% (Talca) to 11% (Santiago), almost three times the number officially reported. Approximately 36% of these were asymptomatic, reaching 82% below 15 years old. Seroprevalence was associated with the city of residence, previous COVID-19 diagnosis, contact with confirmed cases (especially at household), and foreign nationality. The spatial model accurately interpolated the distribution of disease risk within the cities finding significant differences in the predicted probabilities of SARS-CoV-2 infection by census zone (IQR 2.5–15.0%), related to population density and education. Conclusions Our results underscore the transmission heterogeneity of SARS-CoV-2 within and across three urban centers of Chile. Socio-economic factors and the outcomes of this seroprevalence study enable us to identify priority areas for intervention. Our methodological approach and results can help guide the design of interdisciplinary strategies for urban contexts, not only for SARS-CoV-2 but also for other communicable diseases.

No Thumbnail Available
Publication

Respuesta inmunitaria al SARS-CoV-2 y factores asociados previo a la vacunación, en personal de salud de atención primaria en una comuna de Santiago, Chile

2022 , OLEA NORMANDIN, ANDREA MARIA , Elena Pedroni , HIRMAS ADAUY, MACARENA SOLEDAD , MATUTE WILLEMSEM, MARIA ISABEL , IRURETAGOYENA BRUCE, MIRENTXU INES , MUNITA SEPULVEDA, JOSE MANUEL , GONZALEZ WIEDMAIER, CLAUDIA MARTA , María Inés Gómez , Manuel Nájera

No Thumbnail Available
Publication

First wave of SARS-CoV-2 in Santiago Chile: Seroprevalence, asymptomatic infection and infection fatality rate

2022 , VIAL CLARO, PABLO AGUSTIN , GONZALEZ WIEDMAIER, CLAUDIA MARTA , APABLAZA SALINAS, MAURICIO IVÁN , VIAL COX, MARIA CECILIA , Gloria Icaza , ARAOS BRALIC, RAFAEL IGNACIO , RUBILAR RAMIREZ, PAOLA , Juan Correa , Andrei Florea , PEREZ ACUÑA, CLAUDIA VERONICA , Paula Concha , Diego Bastías , María Paz Errázuriz , Ruth Pérez , M.Estela Lavín , OLEA NORMANDIN, ANDREA MARIA , MUNITA SEPULVEDA, JOSE MANUEL , AGUILERA SANHUEZA, XIMENA PAZ , Francisco Guzmán , Eugenio Guzmán

No Thumbnail Available
Publication

From instinct to evidence: the role of data in country decision-making in Chile

2017 , AGUILERA SANHUEZA, XIMENA PAZ , Consuelo Espinosa-Marty , CASTILLO LABORDE, CARLA CECILIA , GONZALEZ WIEDMAIER, CLAUDIA MARTA