CASTILLO LABORDE, CARLA CECILIA
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CASTILLO LABORDE, CARLA CECILIA
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carlacastillo@udd.cl
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Scopus Author ID
36699176800

Research Output

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It Was the Best of Times, It Was the Worst of Times...

2017 , CASTILLO LABORDE, CARLA CECILIA

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Wide percutaneous access to pancreatic necrosis with self-expandable stent: new application (with video)

2011 , Claudio Navarrete , CASTILLO LABORDE, CARLA CECILIA , Mario Caracci , Patricio Vargas , Jaquelina Gobelet , Ignacio Robles

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Barriers and Facilitators in Access to Diabetes, Hypertension, and Dyslipidemia Medicines: A Scoping Review

2022 , CASTILLO LABORDE, CARLA CECILIA , Macarena Hirmas-Adauy , MATUTE WILLEMSEM, MARIA ISABEL , Anita Jasmen , Oscar Urrejola , Xaviera Molina , Camila Awad , Catalina Frey-Moreno , Sofia Pumarino-Lira , Fernando Descalzi-Rojas , Tomás José Ruiz , Barbara Plass

Objective: Identify barriers and facilitators in access to medicines for diabetes, hypertension, and dyslipidemia, considering patient, health provider, and health system perspectives.Methods: Scoping review based on Joanna Briggs methodology. The search considered PubMed, Cochrane Library, CINAHL, Academic Search Ultimate, Web of Science, SciELO Citation Index, and grey literature. Two researchers conducted screening and eligibility phases. Data were thematically analyzed.Results: The review included 219 documents. Diabetes was the most studied condition; most of the evidence comes from patients and the United States. Affordability and availability of medicines were the most reported dimension and specific barrier respectively, both cross-cutting concerns. Among high- and middle-income countries, identified barriers were cost of medicines, accompaniment by professionals, long distances to facilities, and cultural aspects; cost of transportation emerges in low-income settings. Facilitators reported were financial accessibility, trained health workers, medicines closer to communities, and patients’ education.Conclusion: Barriers and facilitators are determined by socioeconomic and cultural conditions, highlighting the role of health systems in regulatory and policy context (assuring financial coverage and free medicines); providers’ role bringing medicines closer; and patients’ health education and disease management.

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Exposure to tobacco impressions during prime-time TV among Chilean minors by sex and socioeconomic status

2022 , PERUGA URREA, ARMANDO , CASTILLO LABORDE, CARLA CECILIA , MATUTE WILLEMSEM, MARIA ISABEL , Xaviera Molina Avendaño , Oscar Urrejola , AGUILERA SANHUEZA, XIMENA PAZ

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Pólipo fibrovascular esofágico: Estudio por imágenes multimodalidad

2010 , CLAUDIO CORTÉS A , DIAZ P., JUAN CARLOS , CLAUDIO NAVARRETE G , CASTILLO LABORDE, CARLA CECILIA , GALLEGOS ANGULO, MARCELA , SILVA FUENTE ALBA, CLAUDIO SERGIO

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Assessment of event-triggered policies of nonpharmaceutical interventions based on epidemiological indicators

2021 , CASTILLO LABORDE, CARLA CECILIA , Taco de Wolff , Pedro Gajardo , Rodrigo Lecaros , Gerard Olivar-Tost , Héctor Ramírez C.

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Pancreatic VIPoma. Report of one case

2010 , Urdangarin, Angélica , Iñiguez, Germán , Benavides, Carlos , CASTILLO LABORDE, CARLA CECILIA , CASTRO MENDEZ, ALEX , Castillo, Iván , Corredoira, Yamile , Close Soto, Néstor

Neuroendocrine tumors are uncommon, including VIPoma that produces vasoactive intestinal polypeptide. We report a 45-year-old female presenting with a history of diarrhea lasting three months. An abdominal CAT scan showed a solid tumor in the body of the pancreas. A fine needle aspiration biopsy of the tumor was compatible with a neuroendocrine tumor. The patient was subjected to a partial pancreatectomy, excising a 4 cm diameter tumor. The pathological study was compatible with a neuroendocrine carcinoma. There was no regional lymph node involvement. During the postoperative period the results of serum vasoactive intestinal polypeptide were received. These were 815.9 pg/ml before surgery and normalized after the operation.

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Rare diseases in Chile: challenges and recommendations in universal health coverage context

2019 , Gonzalo Encina , CASTILLO LABORDE, CARLA CECILIA , LECAROS URZUA, JUAN ALBERTO , Karen Dubois-Camacho , CALDERON GIADROSIC, JUAN FRANCISCO , AGUILERA SANHUEZA, XIMENA PAZ , KLEIN POSTERNACK, ANDRES DAVID , REPETTO LISBOA, MARIA GABRIELA

AbstractRare diseases (RDs) are a large number of diverse conditions with low individual prevalence, but collectively may affect up to 3.5–5.9% of the population. They have psychosocial and economic impact on patients and societies, and are a significant problem for healthcare systems, especially for countries with limited resources. In Chile, financial protection exists for 20 known RDs through different programs that cover diagnosis and treatments. Although beneficial for a number of conditions, most RD patients are left without a proper legal structure that guarantees a financial coverage, and in a vulnerable situation. In this review, we present and analyze the main challenges of the Chilean healthcare system and legislation on RDs, and other ambits of the RD ecosystem, including patient advocacy groups and research. Finally, we propose a set of policy recommendations that includes creating a patient registry, eliciting social preferences on health and financial coverage, improving access to clinical genetic services and therapies, promoting research on RDs and establishing a Latin-American cooperation network, all aimed at promoting equitable quality healthcare access for people living with RDs.

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Mental health consequences of long-term stays in refugee camps: preliminary evidence from Moria

2021 , Willemine van de Wiel , CASTILLO LABORDE, CARLA CECILIA , I. Francisco Urzúa , Michelle Fish , Willem F. Scholte

Abstract Background Ever since the implementation of the EU-Turkey deal, most refugees that enter Greece via sea are confined to the island on which they arrive until their asylum claims are adjudicated, where they generally reside in camps. Some of these camps have detention-like characteristics and dire living conditions, such as Moria camp on the island of Lesbos, Greece. Aid-organizations have stated that the situation in camp Moria deteriorates the mental health of its inhabitants and there is qualitative evidence to support this. This study explores the quantitative relationship between the incidence of acute mental health crises and the length of stay in the camp. Methods A cross-sectional study was conducted using routinely collected data on 856 consultations of 634 different patients during 90 nights at an emergency clinic in Moria camp. Logistic regression analysis was used to explore whether the length of stay in the camp was predictive of the occurrence of an acute mental health crisis. Results Of the 634 patients, the majority were men (59·3%), the average age was 23·2 years [0–71], and 24·3% was < 18 years. 25·5% (n = 218) of consultations were related to mental health problems; 17·0% (n = 37) of these met the study’s case definition of an acute mental health crisis. Such crises were positively associated with the length of stay in the camp (p = 0·011); the odds ratio of a mental health crisis increases with 1·03 for every 10% increase in days of residence in the camp. This is notable when considering the average length of stay in the camp is 71 days. Conclusion This study offers quantitative support for the notion that the adverse conditions in Moria camp deteriorate the mental health of its inhabitants as suggested in qualitative research. Although this study does not provide evidence of causality, it is likely that the poor and unsafe living conditions, challenging refugee determination procedures, and a lack of mental health services in the camp are significant contributing factors. We urgently call for Europe’s policymakers to honour the ‘51 Geneva refugee convention and terminate the neglectful situation on the Greek archipelago.

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From instinct to evidence: the role of data in country decision-making in Chile

2017 , AGUILERA SANHUEZA, XIMENA PAZ , Consuelo Espinosa-Marty , CASTILLO LABORDE, CARLA CECILIA , GONZALEZ WIEDMAIER, CLAUDIA MARTA

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