SLACHEVSKY CHONCHOL, ANDREA MARÍA
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SLACHEVSKY CHONCHOL, ANDREA MARÍA
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Email
aslachevsky@med.uchile.cl
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Scopus Author ID
56394322900

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2024 2024 2023 2023 2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 2016 2016 2015 2015 0 0 2 2 4 4 6 6 8 8 10 10 12 12 14 14
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Impact of the Pandemic Time on the Mental Health of People with Dementia and Their Family Caregivers in Brazil and Chile: One-Year Follow-Up

2024 , Loreto Olavarría , Paulo Caramelli , José Lema , Caíssa Bezerra de Andrade , Alejandra Pinto , Lílian Viana dos Santos Azevedo , Daniela Thumala , Maria Carolina Santos Vieira , Adriana Peredo Rossetti , Alana Barroso Generoso , Karoline Carvalho Carmona , Walter Sepúlveda-Loyola , Ludmilla Aparecida Cardoso Pinto , Maira Tonidandel Barbosa , SLACHEVSKY CHONCHOL, ANDREA MARÍA

Background: Previous studies reported the negative impact of social isolation on mental health in people with dementia (PwD) and their caregivers, butlongitudinal studies seem scarcer. Objective: To describe a one-year follow-up impact of the COVID-19 pandemic on PwD and their caregivers in both Brazil and Chile. Methods: This study analyzed the impact of the pandemic on the psychological and physical health of PwD and their family caregivers after one year of follow-up in three outpatient clinics in Brazil (n = 68) and Chile (n = 61). Results: In both countries, PwD reduced their functional capacity after one year of follow-up (p = 0.017 and p = 0.009; respectively) and caregivers reported worse physical and mental health (p = 0.028 and p = 0.039). Only in Chile, caregivers reported more sadness associated with care (p = 0.001), and reduced time sleeping (p = 0.07). Conclusions: In conclusion, the COVID-19 pandemic appears to have had a long-lasting impact on PwD and their caregivers. However, it is essential to acknowledge that the inherent progression of dementia itself may also influence changes observed over a year.

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Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City

2024 , Ana Luisa Sosa , Sonia MD Brucki , Lucia Crivelli , Francisco Javier Lopera , Daisy M Acosta , Juliana Acosta‐Uribe , Diego Aguilar , Sara G Aguilar‐Navarro , Ricardo F Allegri , Paulo HF Bertolucci , Ismael L Calandri , Maria C Carrillo , Patricio Alexis Chrem Mendez , Mario Cornejo‐Olivas , Nilton Custodio , Andrés Damian , Leonardo Cruz de Souza , Claudia Duran‐Aniotz , Adolfo M García , Carmen García‐Peña , Mitzi M Gonzales , Lea T Grinberg , Agustin M Ibanez , Maryenela Zaida Illanes‐Manrique , Clifford R Jack , Jorge Mario Leon‐Salas , Jorge J Llibre‐Guerra , José Luna‐Muñoz , Diana Matallana , Bruce L Miller , Lorina Naci , Mario A Parra , Margaret Pericak‐Vance , Stefanie D Piña‐Escudero , Elisa de Paula França Resende , John M Ringman , Gustavo Sevlever , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Claudia Kimie Suemoto , Victor Valcour , Andres Villegas‐Lanau , Mônica S Yassuda , Simin Mahinrad , Claire Sexton

AbstractINTRODUCTIONWhile Latin America (LatAm) is facing an increasing burden of dementia due to the rapid aging of the population, it remains underrepresented in dementia research, diagnostics, and care.METHODSIn 2023, the Alzheimer's Association hosted its eighth satellite symposium in Mexico, highlighting emerging dementia research, priorities, and challenges within LatAm.RESULTSSignificant initiatives in the region, including intracountry support, showcased their efforts in fostering national and international collaborations; genetic studies unveiled the unique genetic admixture in LatAm; researchers conducting emerging clinical trials discussed ongoing culturally specific interventions; and the urgent need to harmonize practices and studies, improve diagnosis and care, and use affordable biomarkers in the region was highlighted.DISCUSSIONThe myriad of topics discussed at the 2023 AAIC satellite symposium highlighted the growing research efforts in LatAm, providing valuable insights into dementia biology, genetics, epidemiology, treatment, and care.

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Author Correction: Neurocognitive correlates of semantic memory navigation in Parkinson’s disease

2024 , Felipe Diego Toro-Hernández , Joaquín Migeot , Nicolás Marchant , Daniela Olivares , Franco Ferrante , Raúl González-Gómez , Cecilia González Campo , Sol Fittipaldi , Gonzalo M. Rojas-Costa , Sebastian Moguilner , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Pedro Chaná Cuevas , Agustín Ibáñez , Sergio Chaigneau , Adolfo M. García

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Impact of Social Isolation on People with Dementia and Their Family Caregivers

2021 , Lílian Viana dos Santos Azevedo , Ismael Luis Calandri , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Héctor Gastón Graviotto , Maria Carolina Santos Vieira , Caíssa Bezerra de Andrade , Adriana Peredo Rossetti , Alana Barroso Generoso , Karoline Carvalho Carmona , Ludmilla Aparecida Cardoso Pinto , Marcos Sorbara , Alejandra Pinto , Tania Guajardo , Loreto Olavarria , Daniela Thumala , Lucía Crivelli , Ludmila Vivas , Ricardo Francisco Allegri , Maira Tonidandel Barbosa , Cecilia M. Serrano , Claudia Miranda-Castillo , Paulo Caramelli

Background: People with dementia and their family caregivers may face a great burden through social isolation due to the COVID-19 pandemic, which can be manifested as various behavioral and clinical symptoms. Objective: To investigate the impacts of social isolation due to the COVID-19 pandemic on individuals with dementia and their family caregivers. Methods: Two semi-structured questionnaires were applied via telephone to family caregivers of people diagnosed with dementia in three cities in Argentina, Brazil, and Chile, in order to assess clinical and behavioral changes in people with dementia and in their caregivers. Results: In general, 321 interviews were conducted. A significant decline in memory function has been reported among 53.0%of people with dementia. In addition, 31.2%of individuals with dementia felt sadder and 37.4%had increased anxiety symptoms. These symptoms of anxiety were greater in individuals with mild to moderate dementia, while symptoms of agitation were greater in individuals with severe dementia. Moreover, compulsive-obsessive behavior, hallucinations, increased forgetfulness, altered appetite, and increased difficulty in activities of daily living were reported more frequently among individuals with moderate to severe dementia. Caregivers reported feeling more tired and overwhelmed during this period and these symptoms were also influenced by the severity of dementia. Conclusion: Social isolation during the COVID-19 pandemic triggered a series of negative behavioral repercussions, both for people with dementia and for their family caregivers in these three South American countries.

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Risk factors for loneliness in family caregivers of people with dementia and enduring mental health conditions during the COVID‐19 pandemic in Latin America

2022 , Tomas Leon , Claudia Miranda‐Castillo , Andrea Slachevsky , Thamara Tapia‐Muñoz , Loreto Olavarria , Loreto Castro , Alejandra Pinto , Yaohua Sophie Chen , Iracema Leroi , Brian Lawlor , Claudia Duran‐Aniotz , Emilia Grycuk , Bárbara Costa Beber , Fernando Aguzzoli Peres , Carla Nubia , Pablo Gaitan , Mireya Vilar‐Compte , Roger O'Sullivan

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Aging and Health Policies in Chile: New Agendas for Research

2017 , Daniela Thumala , Brian K. Kennedy , Esteban Calvo , Christian Gonzalez-Billault , Pedro Zitko , Patricia Lillo , Roque Villagra , Agustín Ibáñez , Rodrigo Assar , Maricarmen Andrade , Andrea Slachevsky

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The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds

2023 , Pavel Prado , Vicente Medel , Raul Gonzalez-Gomez , Agustín Sainz-Ballesteros , Victor Vidal , Hernando Santamaría-García , Sebastian Moguilner , Jhony Mejia , SLACHEVSKY CHONCHOL, ANDREA MARÍA , BEHRENS PELLEGRINO, MARIA ISABEL , David Aguillon , Francisco Lopera , Mario A. Parra , Diana Matallana , Marcelo Adrián Maito , Adolfo M. Garcia , Nilton Custodio , Alberto Ávila Funes , Stefanie Piña-Escudero , Agustina Birba , Sol Fittipaldi , Agustina Legaz , Agustín Ibañez

The Latin American Brain Health Institute (BrainLat) has released a unique multimodal neuroimaging dataset of 780 participants from Latin American. The dataset includes 530 patients with neurodegenerative diseases such as Alzheimer’s disease (AD), behavioral variant frontotemporal dementia (bvFTD), multiple sclerosis (MS), Parkinson’s disease (PD), and 250 healthy controls (HCs). This dataset (62.7 ± 9.5 years, age range 21–89 years) was collected through a multicentric effort across five Latin American countries to address the need for affordable, scalable, and available biomarkers in regions with larger inequities. The BrainLat is the first regional collection of clinical and cognitive assessments, anatomical magnetic resonance imaging (MRI), resting-state functional MRI (fMRI), diffusion-weighted MRI (DWI), and high density resting-state electroencephalography (EEG) in dementia patients. In addition, it includes demographic information about harmonized recruitment and assessment protocols. The dataset is publicly available to encourage further research and development of tools and health applications for neurodegeneration based on multimodal neuroimaging, promoting the assessment of regional variability and inclusion of underrepresented participants in research.

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Environmental–genetic interactions in ageing and dementia across Latin America

2024 , Agustin Ibanez , SLACHEVSKY CHONCHOL, ANDREA MARÍA

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Construction and validation of a scale of losses experienced in old age (SLO)

2021 , Daniela Thumala-Dockendorff , Rodrigo Assar , Elisabeth Wenk , Marcelo Arnold-Cathalifaud , Roque Villagra , Patricia Lillo , Andrea Slachevsky

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From Snapshots to Movies: The Association Between Retirement Sequences and Aging Trajectories in Limitations to Perform Activities of Daily Living

2019 , Ariel Azar , Ursula M. Staudinger , Andrea Slachevsky , Ignacio Madero-Cabib , Esteban Calvo

Objective: This study analyzes the dynamic association between retirement sequences and activities of daily living (ADLs) trajectories between ages 60 and 70. Method: Retirement sequences previously established for 7,880 older Americans from the Health and Retirement Study were used in hierarchical linear and propensity score full matching models, analyzing their association with ADL trajectories. Results: Sequences of partial retirement from full- or part-time jobs showed higher baseline and slower decline in ADL than sequences characterized by early labor force disengagement. Discussion: The conventional model in which people completely retire from a full-time job at normative ages and the widely promoted new conventional model of late retirement are both associated with better functioning than early labor force disengagement. But unconventional models, where older adults keep partially engaged with the labor force are also significantly associated with better functioning. These findings call attention to more research on potential avenues to simultaneously promote productive engagement and health later in life.

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