SLACHEVSKY CHONCHOL, ANDREA MARÍA
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SLACHEVSKY CHONCHOL, ANDREA MARÍA
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aslachevsky@med.uchile.cl
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56394322900

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2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 0.0 0.0 0.5 0.5 1.0 1.0 1.5 1.5 2.0 2.0 2.5 2.5 3.0 3.0

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Publication

The cost of dementia in an unequal country: The case of Chile

2017 , Daniel A. Hojman , Fabian Duarte , Jaime Ruiz-Tagle , Marilu Budnich , Carolina Delgado , Andrea Slachevsky , Stefano Federici

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Mapping the neuroanatomy of functional decline in Alzheimer's disease from basic to advanced activities of daily living

2019 , Andrea Slachevsky , Gonzalo Forno , Paulo Barraza , Eneida Mioshi , Carolina Delgado , Patricia Lillo , Henriquez, Fernando , Eduardo Bravo , Mauricio Farias , Carlos Muñoz-Neira , Agustin Ibañez , Mario A. Parra , Michael Hornberger

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Standardization and diagnostic utility of the Frontal Assessment Battery for healthy people and patients with dementia in the Chilean population

2022 , Fabrissio Grandi , David Martínez-Pernía , Mario Parra , Loreto Olavarria , David Huepe , Patricia Alegria , Álvaro Aliaga , Patricia Lillo , Carolina Delgado , Marcela Tenorio , Ricardo Rosas , Oscar López , James Becker , Andrea Slachevsky

ABSTRACT. The Frontal Assessment Battery (FAB) is a screening test that measures executive functions. Although this instrument has been validated in several countries, its diagnostic utility in a Chilean population has not been studied yet. Objectives: This study aimed to (1) adapt FAB in a Chilean population; (2) study the psychometric properties of the FAB in a Chilean population; (3) assess the sociodemographic influence in the performance of the FAB in a sample of healthy controls (HC); and (4) develop normative data for this healthy group. Methods: A HC (n=344) and a group of patients with dementia (n=156) were assessed with the Chilean version of FAB. Results: FAB showed good internal consistency (Cronbach's alpha=0.79) and acceptable validity based on the relationship with other variables. Factor analysis showed the unidimensionality of the instrument. Significant differences were found in the total FAB value between the HC and dementia groups. With the matched sample, the established cutoff point was 13.5, showing a sensitivity of 80.8% and a specificity of 90.4%. Regression analysis showed that education and age significantly predicted FAB performance in the healthy group. Finally, normative data are provided. Conclusions: This study shows that FAB is a useful tool to discriminate between healthy people and people with dementia. However, further studies are needed to explore the capacity of the instrument to characterize the dysexecutive syndrome in people with dementia in the Chilean population.

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Validation of Picture Free and Cued Selective Reminding Test for Illiteracy in Lima, Peru

2022 , Rosa Montesinos , Jose F. Parodi , Monica M. Diaz , Eder Herrera-Perez , Elizabeth Valeriano-Lorenzo , Ambar Soto , Carolina Delgado , Andrea Slachevsky , Nilton Custodio

Dementia in Latin America is a crucial public health problem. Identifying brief cognitive screening (BCS) tools for the primary care setting is crucial, particularly for illiterate individuals. We evaluated tool performance characteristics and validated the free and total recall sections of the Free and Cued Selective Reminding Test-Picture version (FCSRT-Picture) to discriminate between 63 patients with early Alzheimer’s disease dementia (ADD), 60 amnestic mild cognitive impairment (aMCI) and 64 cognitively healthy Peruvian individuals with illiteracy from an urban area. Clinical, functional, and cognitive assessments were performed. FCSRT-Picture performance was assessed using receiver operating characteristic curve analyses. The mean ± standard deviation scores were 7.7 ± 1.0 in ADD, 11.8 ± 1.6 in aMCI, and 29.5 ± 1.8 in controls. The FCSRT-Picture had better performance characteristics for distinguishing controls from aMCI compared with several other BCS tools, but similar characteristics between controls and early ADD. The FCSRT-Picture is a reliable BCS tool for illiteracy in Peru.

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Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease

2017 , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Leonardo Guzmán-Martínez , Carolina Delgado , Pablo Reyes , Gonzalo A. Farías , Carlos Muñoz-Neira , Eduardo Bravo , Mauricio Farías , Patricia Flores , Cristian Garrido , James T. Becker , Oscar L. López , Ricardo B. Maccioni , Paulo Caramelli

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Population attributable fraction of modifiable risk factors for dementia in Chile

2022 , Rodrigo C. Vergara , Pedro Zitko , Andrea Slachevsky , Consuelo San Martin , Carolina Delgado

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