Research Output

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Secondary rectal linitis plastica caused by prostatic adenocarcinoma - magnetic resonance imaging findings and dissemination pathways: A case report

2024 , LABRA WEITZLER, ANDRES ANTONIO , SCHIAPPACASSE FAUNDES, GIANCARLO , Rolando Alfonso Cocio , Jorge Tomás Torres , GONZALEZ COFRE, FERNANDO OMAR , Alberto Cristi , Marcela Schultz

BACKGROUND Secondary rectal linitis plastica (RLP) from prostatic adenocarcinoma is a rare and poorly understood form of metastatic spread, characterized by a desmoplastic response and concentric rectal wall infiltration with mucosal preservation. This complicates endoscopic diagnosis and can mimic gastrointestinal malignancies. This case series underscores the critical role of magnetic resonance imaging (MRI) in identifying the distinct imaging features of RLP and highlights the importance of considering this condition in the differential diagnosis of patients with a history of prostate cancer. CASE SUMMARY Three patients with secondary RLP due to prostatic adenocarcinoma presented with varied clinical features. The first patient, a 76-year-old man with advanced prostate cancer, had rectal pain and incontinence. MRI showed diffuse prostatic invasion and significant rectal wall thickening with a characteristic "target sign" pattern. The second, a 57-year-old asymptomatic man with elevated prostate-specific antigen levels and a history of prostate cancer exhibited rectoprostatic angle involvement and rectal wall thickening on MRI, with positron emission tomography/computed tomography PSMA confirming the prostatic origin of the metastatic spread. The third patient, an 80-year-old post-radical prostatectomy, presented with refractory constipation. MRI revealed a neoplastic mass infiltrating the rectal wall. In all cases, MRI consistently showed stratified thickening, concentric signal changes, restricted diffusion, and contrast enhancement, which were essential for diagnosing secondary RLP. Biopsies confirmed the prostatic origin of the neoplastic involvement in the rectum. CONCLUSION Recognizing MRI findings of secondary RLP is essential for accurate diagnosis and management in prostate cancer patients.

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Caso radiológico de desafío diagnóstico

2014 , Daniel Pérez C. , LABRA WEITZLER, ANDRES ANTONIO , Jorge Pérez G , SCHIAPPACASSE FAUNDES, GIANCARLO , SILVA FUENTE ALBA, CLAUDIO SERGIO

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MRI/TRUS fusion vs. systematic biopsy: intra-patient comparison of diagnostic accuracy for prostate cancer using PI-RADS v2

2020 , Andrés Labra , Claudio Silva , Fernando González , Gerhard Franz , Rodrigo Pinochet , Rajan T. Gupta

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Colangiocarcinoma. Evaluación por Tomografía Computada y Resonancia Magnética

2019 , Lucía Sánchez , LABRA WEITZLER, ANDRES ANTONIO , SCHIAPPACASSE, GIANCARLO

ResumenEl colangiocarcinoma (CC) es el segundo tumor primario maligno más frecuente del hígado. La mayor incidencia se registra en Asia y su pronóstico es poco alentador. La resección quirúrgica del tumor es el único tratamiento potencialmente curativo. Sin embargo, la mayoría de los CC se diagnostican en estadios avanzados de la enfermedad y la recurrencia del tumor es común. Este trabajo pretende demostrar las características imagenológicas de los CC, su clasificación, así como también la evaluación preoperatoria por tomografía computada (TC) y resonancia magnética (RM) que el radiólogo debe realizar actualmente.

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Invaginaciones intestinales en adultos: La visión del radiólogo

2015 , Pablo Alvayay Quilodrán , SCHIAPPACASSE, GIANCARLO , LABRA WEITZLER, ANDRES ANTONIO , Camila De La Barra Escobar

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Interobserver Agreement for the PI-RADS v2 Validation

2019 , LABRA WEITZLER, ANDRES ANTONIO , SILVA FUENTE ALBA, CLAUDIO SERGIO , SCHIAPPACASSE, GIANCARLO , BARAHONA ZULETA, DANIELA FRANCESCA , Skoknic, Velimir

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Manifestaciones abdominales de las anomalías del Situs Ambiguous en el adulto: A propósito de cuatro casos

2013 , Gonzalo Corral G , LABRA WEITZLER, ANDRES ANTONIO , SCHIAPPACASSE FAUNDES, GIANCARLO

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Long-Term Oncological and Functional Outcomes After Robot-Assisted Partial Nephrectomy for Clinically Localized Renal Cell Carcinoma

2022 , Hugo Otaola-Arca , Alfred Krebs , Hugo Bermúdez , Raúl Lyng , Marcelo Orvieto , Alberto Bustamante , Conrado Stein , LABRA WEITZLER, ANDRES ANTONIO , Marcela Schultz , FERNANDEZ ARANCIBIA, MARIO

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Tumores que invaden la vena cava inferior: revisión pictográfica de los principales hallazgos imagenológicos en tomografía computarizada y resonancia magnética

2016 , Matías Molina , SCHIAPPACASSE, GIANCARLO , LABRA WEITZLER, ANDRES ANTONIO

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PI-RADS 2 score utility in clinical practice. Is histologic asses justified? [Utilidad del score PI-RADS 2 en la práctica clínica ¿se justifica el estudio histológico?]

2017 , Andrés Labra W , Juan Pablo Olivares C , María Fernanda Tapia C , Claudio Silva F