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Author: search.filters.author.Caricia PérezSubject: search.filters.subject.adult

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    Campylobacter spp. Prevalence in Santiago, Chile: A Study Based on Molecular Detection in Clinical Stool Samples from 2014 to 2019
    (2023)
    PORTE TORRE, LORENA ISABEL  
    ;
    Caricia Pérez
    ;
    Mario Barbé
    ;
    Carmen Varela
    ;
    Valeska Vollrath
    <jats:p>Campylobacter spp. is an emerging cause of infectious diarrhea worldwide. In South American countries such as Chile, its prevalence is underestimated due to inadequate detection methods. Gastrointestinal multiplex PCR panels (GMP) permit rapid and sensitive detection of bacterial pathogens and provide important epidemiological information. This study aimed to analyze Campylobacter epidemiology using the results of molecular methods and to compare molecular detection results to those of culture methods. We performed a retrospective, descriptive analysis of Campylobacter spp. detected in clinical stool samples between 2014–2019 by GMP and culture. Within 16,582 specimens examined by GMP, Campylobacter was the most prevalent enteropathogenic bacteria (8.5%), followed by Salmonella spp. (3.9%), Shigella spp./enteroinvasive Escherichia coli (EIEC) (1.9%), and Yersinia enterocolitica (0.8%). The highest Campylobacter prevalence occurred in 2014/2015. Campylobacteriosis affected more males (57.2%) and adults from 19–65 years (47.9%) and showed a bimodal seasonality with summer and winter peaks. In 11,251 routine stool cultures, Campylobacter spp. was detected in 4.6%, mostly C. jejuni (89.6%). Among 4533 samples tested by GMP and culture in parallel, GMP showed a superior sensitivity (99.1% versus 50%, respectively). The study suggests that Campylobacter spp. is the most frequent bacterial enteropathogen in Chile.</jats:p>
      1Scopus© Citations 6  1
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    Item type:Publication,
    Novel Vector of Scrub Typhus in Sub-Antarctic Chile: Evidence From Human Exposure
    (2021)
    WEITZEL, THOMAS  
    ;
    María Carolina Silva-de la Fuente
    ;
    Constanza Martínez-Valdebenito
    ;
    Alexandr A Stekolnikov
    ;
    Caricia Pérez
    <jats:title>Abstract</jats:title> <jats:p>The exposure of a research team to chigger mites in southern Chile allowed the first identification of a trombiculid species as vector and reservoir of scrub typhus outside the tsutsugamushi triangle, providing unique insights into the ecology and transmission of this recently discovered rickettsial infection in South America.</jats:p>
    Scopus© Citations 22  5